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GENE:
MET (MET proto-oncogene, receptor tyrosine kinase)
i
Other names:
DFNB97, AUTS9, RCCP2, C-Met, HGFR, HGF Receptor, Met Proto-Oncogene, HGF/SF Receptor, Proto-Oncogene C-Met, Scatter Factor Receptor, Tyrosine-Protein Kinase Met, Hepatocyte Growth Factor Receptor, MET, MET Proto-Oncogene, Receptor Tyrosine Kinase
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Entrez ID:
4233
Related tests:
‹
FoundationOne® CDx (110)
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FoundationOne® Liquid CDx (21)
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Oncomine™ Dx Target Test (10)
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Oncomine™ Pan-Cancer Cell-Free Assay (4)
TruSight Oncology 500 Assay (3)
Guardant360 TissueNext™ (2)
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Oncomine™ Comprehensive Assay v3M (2)
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ArcherMET (1)
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AVENIO Tumor Tissue CGP Kit
AVENIO Tumor Tissue Surveillance Kit
AVENIO Tumor Tissue Targeted Kit
AVENIO ctDNA Surveillance Kit
AVENIO ctDNA Targeted Kit
AmoyDx MET Mutation Detection Kit
AmoyDx® Essential NGS Panel
AmoyDx® HANDLE Classic NGS Panel
AmoyDx® Master Panel
AnchorAIM® 10 Gene Test for Individualized Treatment of Lung Cancer
AnchorAIM® 72 gene detection for individualized treatment of solid tumors
Archer® FusionPlex® Lung Kit
Archer® VariantPlex® Comprehensive Thyroid and Lung (CTL) kit
Archer® VariantPlex® Solid Tumor Kit
Archer™ FusionPlex™ Core Solid Tumor Panel
Archer™ VARIANTPlex™ Complete Solid Tumor panel
Archer™ VARIANTPlex™ Pan Solid Tumor panel
BROCA Cancer Risk Panel
Blueprint Genetics Comprehensive Hereditary Cancer Panel
CELsignia test
CancerNext-Expanded®
CustomNext-Cancer®
Droplex c-Met Exon14 Skipping Test
Find It®
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FusionPlex® Dx
FusionPlex® Pan Solid Tumor v2 panel
GALEAS™ Hereditary Plus
HDPCR NSCLC RUO Assay
InVisionSeq™
Ion AmpliSeq Colon and Lung Cancer Research Panel v2
Labcorp® Plasma Complete™
Labcorp® Plasma Focus™
Liquid Trace™ Solid Tumor
LiquidGx™
LiquidHALLMARK®
LiquidPlex™
Lung Cancer 8-Gene Kit
LungCure™ CDx
NGS Targeted Hotspot Panel
NeXT Dx™ Test
NeoLAB® Solid Tumor Liquid Biopsy
NeoTYPE® Lung Tumor Profile
Northstar Select™
NovoFocus™ CRC 2.0
NovoFocus™ NSCLC 2.0 Test
OncoGuide™ NCC Oncopanel System
OncoKey™ SL 60 Plus Assay
OncoPanel™ Assay
OncoSTRAT&GO
OncoScreen™ Focus CDx Tissue Kit
Oncomine Dx Express Test
Oncomine Focus Assay
Oncomine Lung Cell-Free Total Nucleic Acid Research Assay
Oncomine Precision Assay
Oncomine™ Comprehensive Assay Plus
Oncomine™ Lung cfDNA Assay
Oncotype MAP™ Pan-Cancer Tissue Test
OptiSeq™ Colorectal Cancer Panel
OptiSeq™ Lung Cancer Panel
OptiSeq™ Pan-Cancer Gene Panel
PGDx elio™ plasma resolve assay
PredicineCARE™
RenalNext™
SOPHiA DDM Dx RNAtarget Oncology Solution
SOPHiA DDM™ Solid Tumor Plus Solution
Solid Tumor Profile Plus
StrataNGS™ Test
Target Selector™ NGS Lung Panel
Tempus xF+ Panel
Tempus xG+
Tempus xR
TruSight Oncology Comprehensive
TruSight Tumor 15 Assay
TruSight Tumor 170 Assay
VarMap™ Pan-Cancer NGS Panel
oncoReveal™ Core LBx
oncoReveal™ Essential LBx
oncoReveal™ Fusion LBx Panel
oncoReveal™ Multi-Cancer with CNV & RNA Fusion Panel
oncoReveal™ Solid Tumor v2 Panel
FoundationOne® CDx (110)
Guardant360® CDx (54)
FoundationOne® Liquid CDx (21)
MSK-IMPACT (21)
Oncomine™ Dx Target Test (10)
TruSeq®Amplicon - Cancer Panel (5)
Oncomine™ Pan-Cancer Cell-Free Assay (4)
TruSight Oncology 500 Assay (3)
Guardant360 TissueNext™ (2)
HTG EdgeSeq Oncology Biomarker Panel (OBP) (2)
Oncomine™ Comprehensive Assay v3M (2)
AmoyDx® Pan Lung Cancer PCR Panel (1)
ArcherMET (1)
Archer® FusionPlex® Comprehensive Thyroid & Lung (CTL) Kit (1)
Idylla™ GeneFusion Assay (1)
InVisionFirst®-Lung (1)
ACTOnco
ASPYRE-Lung
AVENIO Tumor Tissue CGP Kit
AVENIO Tumor Tissue Surveillance Kit
AVENIO Tumor Tissue Targeted Kit
AVENIO ctDNA Surveillance Kit
AVENIO ctDNA Targeted Kit
AmoyDx MET Mutation Detection Kit
AmoyDx® Essential NGS Panel
AmoyDx® HANDLE Classic NGS Panel
AmoyDx® Master Panel
AnchorAIM® 10 Gene Test for Individualized Treatment of Lung Cancer
AnchorAIM® 72 gene detection for individualized treatment of solid tumors
Archer® FusionPlex® Lung Kit
Archer® VariantPlex® Comprehensive Thyroid and Lung (CTL) kit
Archer® VariantPlex® Solid Tumor Kit
Archer™ FusionPlex™ Core Solid Tumor Panel
Archer™ VARIANTPlex™ Complete Solid Tumor panel
Archer™ VARIANTPlex™ Pan Solid Tumor panel
BROCA Cancer Risk Panel
Blueprint Genetics Comprehensive Hereditary Cancer Panel
CELsignia test
CancerNext-Expanded®
CustomNext-Cancer®
Droplex c-Met Exon14 Skipping Test
Find It®
Follow It®
FusionPlex® Dx
FusionPlex® Pan Solid Tumor v2 panel
GALEAS™ Hereditary Plus
HDPCR NSCLC RUO Assay
InVisionSeq™
Ion AmpliSeq Colon and Lung Cancer Research Panel v2
Labcorp® Plasma Complete™
Labcorp® Plasma Focus™
Liquid Trace™ Solid Tumor
LiquidGx™
LiquidHALLMARK®
LiquidPlex™
Lung Cancer 8-Gene Kit
LungCure™ CDx
NGS Targeted Hotspot Panel
NeXT Dx™ Test
NeoLAB® Solid Tumor Liquid Biopsy
NeoTYPE® Lung Tumor Profile
Northstar Select™
NovoFocus™ CRC 2.0
NovoFocus™ NSCLC 2.0 Test
OncoGuide™ NCC Oncopanel System
OncoKey™ SL 60 Plus Assay
OncoPanel™ Assay
OncoSTRAT&GO
OncoScreen™ Focus CDx Tissue Kit
Oncomine Dx Express Test
Oncomine Focus Assay
Oncomine Lung Cell-Free Total Nucleic Acid Research Assay
Oncomine Precision Assay
Oncomine™ Comprehensive Assay Plus
Oncomine™ Lung cfDNA Assay
Oncotype MAP™ Pan-Cancer Tissue Test
OptiSeq™ Colorectal Cancer Panel
OptiSeq™ Lung Cancer Panel
OptiSeq™ Pan-Cancer Gene Panel
PGDx elio™ plasma resolve assay
PredicineCARE™
RenalNext™
SOPHiA DDM Dx RNAtarget Oncology Solution
SOPHiA DDM™ Solid Tumor Plus Solution
Solid Tumor Profile Plus
StrataNGS™ Test
Target Selector™ NGS Lung Panel
Tempus xF+ Panel
Tempus xG+
Tempus xR
TruSight Oncology Comprehensive
TruSight Tumor 15 Assay
TruSight Tumor 170 Assay
VarMap™ Pan-Cancer NGS Panel
oncoReveal™ Core LBx
oncoReveal™ Essential LBx
oncoReveal™ Fusion LBx Panel
oncoReveal™ Multi-Cancer with CNV & RNA Fusion Panel
oncoReveal™ Solid Tumor v2 Panel
›
Associations
(320)
News
Trials
VERI cancer hierarchy
Reset Filters
MET exon 14 mutation
Non Small Cell Lung Cancer
MET exon 14 mutation
Non Small Cell Lung Cancer
tepotinib
Sensitive: A1 - Approval
tepotinib
Sensitive
:
A1
tepotinib
Sensitive: A1 - Approval
tepotinib
Sensitive
:
A1
MET exon 14 mutation
Non Small Cell Lung Cancer
MET exon 14 mutation
Non Small Cell Lung Cancer
capmatinib
Sensitive: A1 - Approval
capmatinib
Sensitive
:
A1
capmatinib
Sensitive: A1 - Approval
capmatinib
Sensitive
:
A1
MET exon 14 mutation
Non Small Cell Lung Cancer
MET exon 14 mutation
Non Small Cell Lung Cancer
savolitinib
Sensitive: A1 - Approval
savolitinib
Sensitive
:
A1
savolitinib
Sensitive: A1 - Approval
savolitinib
Sensitive
:
A1
MET exon 14 mutation
Non Small Cell Lung Cancer
MET exon 14 mutation
Non Small Cell Lung Cancer
APL-101
Sensitive: A1 - Approval
APL-101
Sensitive
:
A1
APL-101
Sensitive: A1 - Approval
APL-101
Sensitive
:
A1
MET exon 14 mutation
Non Small Cell Lung Cancer
MET exon 14 mutation
Non Small Cell Lung Cancer
gumarontinib
Sensitive: A1 - Approval
gumarontinib
Sensitive
:
A1
gumarontinib
Sensitive: A1 - Approval
gumarontinib
Sensitive
:
A1
MET amplification
Non Small Cell Lung Cancer
MET amplification
Non Small Cell Lung Cancer
crizotinib
Sensitive: A2 - Guideline
crizotinib
Sensitive
:
A2
crizotinib
Sensitive: A2 - Guideline
crizotinib
Sensitive
:
A2
MET exon 14 mutation
Non Small Cell Lung Cancer
MET exon 14 mutation
Non Small Cell Lung Cancer
crizotinib
Sensitive: A2 - Guideline
crizotinib
Sensitive
:
A2
crizotinib
Sensitive: A2 - Guideline
crizotinib
Sensitive
:
A2
MET amplification
Non Small Cell Lung Cancer
MET amplification
Non Small Cell Lung Cancer
tepotinib
Sensitive: A2 - Guideline
tepotinib
Sensitive
:
A2
tepotinib
Sensitive: A2 - Guideline
tepotinib
Sensitive
:
A2
MET amplification
Renal Cell Carcinoma
MET amplification
Renal Cell Carcinoma
savolitinib
Sensitive: A2 - Guideline
savolitinib
Sensitive
:
A2
savolitinib
Sensitive: A2 - Guideline
savolitinib
Sensitive
:
A2
MET expression
Gastroesophageal Junction Adenocarcinoma
MET expression
Gastroesophageal Junction Adenocarcinoma
AMG 102
Resistant: B - Late Trials
AMG 102
Resistant
:
B
AMG 102
Resistant: B - Late Trials
AMG 102
Resistant
:
B
MET amplification
Gastroesophageal Junction Adenocarcinoma
MET amplification
Gastroesophageal Junction Adenocarcinoma
AMG 102
Resistant: B - Late Trials
AMG 102
Resistant
:
B
AMG 102
Resistant: B - Late Trials
AMG 102
Resistant
:
B
MET expression
Gastric Adenocarcinoma
MET expression
Gastric Adenocarcinoma
AMG 102
Resistant: B - Late Trials
AMG 102
Resistant
:
B
AMG 102
Resistant: B - Late Trials
AMG 102
Resistant
:
B
MET amplification
Gastric Adenocarcinoma
MET amplification
Gastric Adenocarcinoma
AMG 102
Resistant: B - Late Trials
AMG 102
Resistant
:
B
AMG 102
Resistant: B - Late Trials
AMG 102
Resistant
:
B
MET mutation
Renal Cell Carcinoma
MET mutation
Renal Cell Carcinoma
savolitinib
Sensitive: B - Late Trials
savolitinib
Sensitive
:
B
savolitinib
Sensitive: B - Late Trials
savolitinib
Sensitive
:
B
EGFR wild-type + MET overexpression
Lung Non-Squamous Non-Small Cell Cancer
EGFR wild-type + MET overexpression
Lung Non-Squamous Non-Small Cell Cancer
ABBV-399
Sensitive: B - Late Trials
ABBV-399
Sensitive
:
B
ABBV-399
Sensitive: B - Late Trials
ABBV-399
Sensitive
:
B
MET overexpression + KDR overexpression
Ovarian Cancer
MET overexpression + KDR overexpression
Ovarian Cancer
bevacizumab
Resistant: B - Late Trials
bevacizumab
Resistant
:
B
bevacizumab
Resistant: B - Late Trials
bevacizumab
Resistant
:
B
MET elevation
Hepatocellular Cancer
MET elevation
Hepatocellular Cancer
cabozantinib tablet
Resistant: B - Late Trials
cabozantinib tablet
Resistant
:
B
cabozantinib tablet
Resistant: B - Late Trials
cabozantinib tablet
Resistant
:
B
MET overexpression
Non Small Cell Lung Cancer
MET overexpression
Non Small Cell Lung Cancer
MYTX-011
Sensitive: B - Late Trials
MYTX-011
Sensitive
:
B
MYTX-011
Sensitive: B - Late Trials
MYTX-011
Sensitive
:
B
MET exon 14 mutation
Lung Adenocarcinoma
MET exon 14 mutation
Lung Adenocarcinoma
tepotinib
Sensitive: C1 - Off-label
tepotinib
Sensitive
:
C1
tepotinib
Sensitive: C1 - Off-label
tepotinib
Sensitive
:
C1
MET exon 14 mutation
Lung Adenocarcinoma
MET exon 14 mutation
Lung Adenocarcinoma
capmatinib
Sensitive: C1 - Off-label
capmatinib
Sensitive
:
C1
capmatinib
Sensitive: C1 - Off-label
capmatinib
Sensitive
:
C1
MET exon 14 mutation
Lung Adenocarcinoma
MET exon 14 mutation
Lung Adenocarcinoma
savolitinib
Sensitive: C1 - Off-label
savolitinib
Sensitive
:
C1
savolitinib
Sensitive: C1 - Off-label
savolitinib
Sensitive
:
C1
MET exon 14 mutation
Gastric Cancer
MET exon 14 mutation
Gastric Cancer
tepotinib
Sensitive: C1 - Off-label
tepotinib
Sensitive
:
C1
tepotinib
Sensitive: C1 - Off-label
tepotinib
Sensitive
:
C1
MET amplification
Non Small Cell Lung Cancer
MET amplification
Non Small Cell Lung Cancer
bevacizumab + crizotinib
Sensitive: C2 – Inclusion Criteria
bevacizumab + crizotinib
Sensitive
:
C2
bevacizumab + crizotinib
Sensitive: C2 – Inclusion Criteria
bevacizumab + crizotinib
Sensitive
:
C2
MET amplification
Non Small Cell Lung Cancer
MET amplification
Non Small Cell Lung Cancer
gumarontinib
Sensitive: C2 – Inclusion Criteria
gumarontinib
Sensitive
:
C2
gumarontinib
Sensitive: C2 – Inclusion Criteria
gumarontinib
Sensitive
:
C2
MET amplification
Non Small Cell Lung Cancer
MET amplification
Non Small Cell Lung Cancer
gefitinib + CT053PTSA
Sensitive: C2 – Inclusion Criteria
gefitinib + CT053PTSA
Sensitive
:
C2
gefitinib + CT053PTSA
Sensitive: C2 – Inclusion Criteria
gefitinib + CT053PTSA
Sensitive
:
C2
MET amplification
Gastric Cancer
MET amplification
Gastric Cancer
TPX-0022
Sensitive: C2 – Inclusion Criteria
TPX-0022
Sensitive
:
C2
TPX-0022
Sensitive: C2 – Inclusion Criteria
TPX-0022
Sensitive
:
C2
MET mutation
Gastric Cancer
MET mutation
Gastric Cancer
TPX-0022
Sensitive: C2 – Inclusion Criteria
TPX-0022
Sensitive
:
C2
TPX-0022
Sensitive: C2 – Inclusion Criteria
TPX-0022
Sensitive
:
C2
MET amplification
Non Small Cell Lung Cancer
MET amplification
Non Small Cell Lung Cancer
osimertinib + savolitinib
Sensitive: C2 – Inclusion Criteria
osimertinib + savolitinib
Sensitive
:
C2
osimertinib + savolitinib
Sensitive: C2 – Inclusion Criteria
osimertinib + savolitinib
Sensitive
:
C2
MET amplification
Lung Cancer
MET amplification
Lung Cancer
tepotinib
Sensitive: C2 – Inclusion Criteria
tepotinib
Sensitive
:
C2
tepotinib
Sensitive: C2 – Inclusion Criteria
tepotinib
Sensitive
:
C2
MET amplification
Non Small Cell Lung Cancer
MET amplification
Non Small Cell Lung Cancer
APL-101
Sensitive: C2 – Inclusion Criteria
APL-101
Sensitive
:
C2
APL-101
Sensitive: C2 – Inclusion Criteria
APL-101
Sensitive
:
C2
MET positive
Solid Tumor
MET positive
Solid Tumor
GST-HG16
Sensitive: C2 – Inclusion Criteria
GST-HG16
Sensitive
:
C2
GST-HG16
Sensitive: C2 – Inclusion Criteria
GST-HG16
Sensitive
:
C2
MET mutation
Non Small Cell Lung Cancer
MET mutation
Non Small Cell Lung Cancer
crizotinib
Sensitive: C2 – Inclusion Criteria
crizotinib
Sensitive
:
C2
crizotinib
Sensitive: C2 – Inclusion Criteria
crizotinib
Sensitive
:
C2
^
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