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Follow It®

Laboratory Developed Test
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Follow It is an amplicon-based focused liquid biopsy panel that analyzes cell-free circulating tumor DNA (ctDNA) in plasma isolated from peripheral blood. The assay is designed to detect SNVs and CNVs commonly associated with multiple solid tumor types, as well as MSI-status. Follow It detects common, clinically relevant genomic alterations in solid tumor samples, including single-base substitutions (SNVs), small deletions, and insertions (up to 24bp). It evaluates the mutation status of tumor DNA at 337 hotspots and 26 exons in 38 known cancer-associated genes simultaneously.
Basal Cell Carcinoma, Breast Cancer, Colorectal Cancer, Endometrial Cancer, Gastrointestinal Stromal Tumor, Melanoma, Non Small Cell Lung Cancer, Solid Tumor
AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), AR (Androgen receptor), BRAF (B-raf proto-oncogene), CTNNB1 (Catenin (cadherin-associated protein), beta 1), DDR2 (Discoidin domain receptor 2)
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Liquid biopsy