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BROCA Cancer Risk Panel

Laboratory Developed Test
Related tests:


BROCA is useful for the evaluation of patients with a suspected hereditary cancer predisposition, with a focus on syndromes that include breast or ovarian cancer as one of the cancer types. Depending on the causative gene involved, these cancers may co-occur with other cancer types (such as colorectal, endometrial, pancreatic, endocrine, or melanoma). BROCA uses next-generation sequencing to detect most mutations. The assay completely sequences all exons of these genes AND detects large deletions and duplications.
Breast Cancer, Colorectal Cancer, Endocrine Cancer, Endometrial Cancer, Melanoma, Ovarian Cancer, Pancreatic Cancer
AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), ATM (ATM serine/threonine kinase), ATR (Ataxia telangiectasia and Rad3-related protein), BAP1 (BRCA1 Associated Protein 1)
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Next-Generation Sequencing (NGS)