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our Premium Content: News alerts, weekly reports and conference plannersTEST:Ion AmpliSeq Colon and Lung Cancer Research Panel v2
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News alerts, weekly reports and conference planners
Company:
Thermo Fisher ScientificType:
Laboratory Developed Test
Related tests:
The Ion AmpliSeq Colon and Lung Cancer Research Panel v2 has primer pairs in a single pool for hotspots and targeted regions for 22 known genes associated with colon and lung tumor tissue. In addition, the
panel now also includes primers for 3 additional amplicons covering target regions of the NRAS and ALK genes: NRAS exon 4 variants (p.117, p.146), ALK variants (G1269A, p.S1206Y). The first version of the panel, the Ion AmpliSeq Colon and Lung Cancer Research Panel, was tested and verified by the OncoNetwork Consortium, with 155 unique FFPE samples. The Ion AmpliSeq Colon and Lung Cancer
Research Panel v2 is ready-to-use and optimized for data analysis with Torrent Suite and Ion Reporter Software.
Cancer:
Colon Cancer, Lung Cancer
Gene:
AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), BRAF (B-raf proto-oncogene), CTNNB1 (Catenin (cadherin-associated protein), beta 1), DDR2 (Discoidin domain receptor 2), EGFR (Epidermal growth factor receptor)
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AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), BRAF (B-raf proto-oncogene), CTNNB1 (Catenin (cadherin-associated protein), beta 1), DDR2 (Discoidin domain receptor 2), EGFR (Epidermal growth factor receptor), ERBB4 (erb-b2 receptor tyrosine kinase 4), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), HER-2 (Human epidermal growth factor receptor 2), KRAS (KRAS proto-oncogene GTPase), MAP2K1 (Mitogen-activated protein kinase kinase 1), MET (MET proto-oncogene, receptor tyrosine kinase), NOTCH1 (Notch 1), NRAS (Neuroblastoma RAS viral oncogene homolog), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), PTEN (Phosphatase and tensin homolog), SMAD4 (SMAD family member 4), STK11 (Serine/threonine kinase 11), TP53 (Tumor protein P53)
