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our Premium Content: News alerts, weekly reports and conference plannersTEST:Archer™ FusionPlex™ Core Solid Tumor Panel
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News alerts, weekly reports and conference planners
Company:
Integrated DNA TechnologiesType:
Laboratory Developed Test
Related tests:
Archer’s FusionPlex Core Solid Tumor panel enables simultaneous detection of fusions, splice variants, key SNV/Indels, and relative RNA expression from the same input to drive cost efficiency. The panel features expanded SNV/Indel coverage over key genes, including tumor suppressors. With Anchored Multiplex PCR (AMP™) chemistry at the core and an integrated bioinformatic platform, FusionPlex targeted NGS assays offer streamlined RNA-based analysis from sample to data.
Cancer:
Solid Tumor
Gene:
AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), AXL (AXL Receptor Tyrosine Kinase), BRAF (B-raf proto-oncogene), BRD3 (Bromodomain Containing 3), BRD4 (Bromodomain Containing 4)
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AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), AXL (AXL Receptor Tyrosine Kinase), BRAF (B-raf proto-oncogene), BRD3 (Bromodomain Containing 3), BRD4 (Bromodomain Containing 4), CTNNB1 (Catenin (cadherin-associated protein), beta 1), CYSLTR2 (Cysteinyl Leukotriene Receptor 2), DNAJB1 (DnaJ Heat Shock Protein Family (Hsp40) Member B1), EGFR (Epidermal growth factor receptor), ER (Estrogen receptor), ERBB4 (erb-b2 receptor tyrosine kinase 4), ERG (ETS Transcription Factor ERG), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), GNA11 (G Protein Subunit Alpha 11), GNAQ (G Protein Subunit Alpha Q), GNAS (GNAS Complex Locus), H3F3A (H3 Histone Family Member 3A), HER-2 (Human epidermal growth factor receptor 2), HRAS (Harvey rat sarcoma viral oncogene homolog), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), KEAP1 (Kelch Like ECH Associated Protein 1), KIT (KIT proto-oncogene, receptor tyrosine kinase), KRAS (KRAS proto-oncogene GTPase), LTK (Leukocyte Receptor Tyrosine Kinase), MAP2K1 (Mitogen-activated protein kinase kinase 1), MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8), MET (MET proto-oncogene, receptor tyrosine kinase), MYB (MYB Proto-Oncogene, Transcription Factor), MYBL1 (MYB Proto-Oncogene Like 1), NRAS (Neuroblastoma RAS viral oncogene homolog), NRG1 (Neuregulin 1), NTRK1 (Neurotrophic tyrosine kinase, receptor, type 1), NTRK2 (Neurotrophic tyrosine kinase, receptor, type 2), NTRK3 (Neurotrophic tyrosine kinase, receptor, type 3), NUTM1 (NUT Midline Carcinoma Family Member 1), PAX8 (Paired box 8), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), POLD1 (DNA Polymerase Delta 1), POLE (DNA Polymerase Epsilon), PPARG (Peroxisome Proliferator Activated Receptor Gamma), PRKCA (Protein Kinase C Alpha), PRKCB (Protein Kinase C Beta), RAF1 (Raf-1 Proto-Oncogene Serine/Threonine Kinase), RET (Ret Proto-Oncogene), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), STK11 (Serine/threonine kinase 11), TMPRSS2 (Transmembrane serine protease 2), TP53 (Tumor protein P53)
Method:
Next-Generation Sequencing (NGS)
