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our Premium Content: News alerts, weekly reports and conference plannersTEST:TruSeq®Amplicon - Cancer Panel
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Company:
IlluminaType:
Laboratory Developed Test
Related tests:
The TruSeq Amplicon - Cancer Panel (TSACP) is a highly multiplexed targeted resequencing assay for detecting somatic mutations across hundreds of mutational hotspots in cancer genomes. TSACP
provides a streamlined workflow, including a quality control assay for DNA from formalin-fixed, paraffin-embedded (FFPE) samples, simple bead-based sample normalization, automated cluster generation and paired-end sequencing, and on-instrument data analysis. TSACP enables highly sensitive mutation detection within important genes, including BRAF, KRAS, and EGFR.
Cancer:
Triple Negative Breast Cancer
Gene:
ABL1 (ABL proto-oncogene 1), ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), ATM (ATM serine/threonine kinase), BRAF (B-raf proto-oncogene), CDH1 (Cadherin 1)
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ABL1 (ABL proto-oncogene 1), ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), ATM (ATM serine/threonine kinase), BRAF (B-raf proto-oncogene), CDH1 (Cadherin 1), CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), CSF1R (Colony stimulating factor 1 receptor), CTNNB1 (Catenin (cadherin-associated protein), beta 1), EGFR (Epidermal growth factor receptor), ERBB4 (erb-b2 receptor tyrosine kinase 4), FBXW7 (F-Box And WD Repeat Domain Containing 7), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), FLT3 (Fms-related tyrosine kinase 3), GNA11 (G Protein Subunit Alpha 11), GNAQ (G Protein Subunit Alpha Q), GNAS (GNAS Complex Locus), HER-2 (Human epidermal growth factor receptor 2), HRAS (Harvey rat sarcoma viral oncogene homolog), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), JAK2 (Janus kinase 2), JAK3 (Janus Kinase 3), KIT (KIT proto-oncogene, receptor tyrosine kinase), KRAS (KRAS proto-oncogene GTPase), MET (MET proto-oncogene, receptor tyrosine kinase), MLH1 (MutL homolog 1), NOTCH1 (Notch 1), NRAS (Neuroblastoma RAS viral oncogene homolog), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PTEN (Phosphatase and tensin homolog)
Method:
Targeted Gene Sequencing (TGS)
