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    TEST:
    AmoyDx® Pan Lung Cancer PCR Panel

    Company:
    Amoy Diagnostics
    Type:
    Other Approval
    Related tests:
    AmoyDx Pan Lung Cancer Panel is qualitative detection of 167 hotspot alterations in EGFR, ALK, ROS1, KRAS, BRAF, HER2, RET, MET, NTRK1, NTRK2 and NTRK3 genes in NSCLC at a time from a single tissue specimen. The assay contains DNA-based mutation detection and mRNA-based fusion detection. The RNA gene fusion detection includes two processes: 1) Reverse Transcription, 2) PCR Amplification. The DNA gene mutation detection system uses ADx-ARMS technology.
    Cancer:
    Non Small Cell Lung Cancer
    Gene:
    ALK (Anaplastic lymphoma kinase), BRAF (B-raf proto-oncogene), EGFR (Epidermal growth factor receptor), HER-2 (Human epidermal growth factor receptor 2), KRAS (KRAS proto-oncogene GTPase), MET (MET proto-oncogene, receptor tyrosine kinase)
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    Drug:
    Lumakras (sotorasib), Retevmo (selpercatinib), Rozlytrek (entrectinib), Tepmetko (tepotinib), gumarontinib (SCC244)
    Method:
    RT-PCR