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TEST:
AmoyDx® Pan Lung Cancer PCR Panel

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Company:

Amoy Diagnostics

Type:

Other Approval

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AmoyDx® Essential NGS Panel

AmoyDx® HANDLE Classic NGS Panel

AmoyDx® HANDLE HRR NGS Panel

AmoyDx® HER2 Mutation Detection Kit

AmoyDx® Human Papillomavirus (HPV) Genotyping Detection Kit

AmoyDx® JAK2 Mutation Detection Kit

AmoyDx® KRAS Mutation Detection Kit

AmoyDx® KRAS/NRAS Mutations Detection Kit

AmoyDx® Master Panel

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AmoyDx Pan Lung Cancer Panel is qualitative detection of 167 hotspot alterations in EGFR, ALK, ROS1, KRAS, BRAF, HER2, RET, MET, NTRK1, NTRK2 and NTRK3 genes in NSCLC at a time from a single tissue specimen. The assay contains DNA-based mutation detection and mRNA-based fusion detection. The RNA gene fusion detection includes two processes: 1) Reverse Transcription, 2) PCR Amplification. The DNA gene mutation detection system uses ADx-ARMS technology.

Cancer:

Non Small Cell Lung Cancer

Gene:

ALK (Anaplastic lymphoma kinase), BRAF (B-raf proto-oncogene), EGFR (Epidermal growth factor receptor), HER-2 (Human epidermal growth factor receptor 2), KRAS (KRAS proto-oncogene GTPase), MET (MET proto-oncogene, receptor tyrosine kinase)

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Drug:

Lumakras (sotorasib), Rozlytrek (entrectinib), Tepmetko (tepotinib), gumarontinib (SCC244)

Method:

RT-PCR