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TEST:
AmoyDx® Pan Lung Cancer PCR Panel

Type:
Other Approval
Related tests:
AmoyDx Pan Lung Cancer Panel is qualitative detection of 167 hotspot alterations in EGFR, ALK, ROS1, KRAS, BRAF, HER2, RET, MET, NTRK1, NTRK2 and NTRK3 genes in NSCLC at a time from a single tissue specimen. The assay contains DNA-based mutation detection and mRNA-based fusion detection. The RNA gene fusion detection includes two processes: 1) Reverse Transcription, 2) PCR Amplification. The DNA gene mutation detection system uses ADx-ARMS technology.
Cancer:
Non Small Cell Lung Cancer
Gene:
ALK (Anaplastic lymphoma kinase), BRAF (B-raf proto-oncogene), EGFR (Epidermal growth factor receptor), HER-2 (Human epidermal growth factor receptor 2), KRAS (KRAS proto-oncogene GTPase), MET (MET proto-oncogene, receptor tyrosine kinase)
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Drug:
Haiyitan (gumarontinib), Lumakras (sotorasib), Retevmo (selpercatinib), Rozlytrek (entrectinib), Tabrecta (capmatinib), Tepmetko (tepotinib)
Method:
RT-PCR