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our Premium Content: News alerts, weekly reports and conference plannersTEST:oncoReveal™ Multi-Cancer with CNV & RNA Fusion Panel
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News alerts, weekly reports and conference planners
Company:
Pillar BiosciType:
Laboratory Developed Test
Related tests:
The oncoReveal Multi-Cancer with CNV & RNA Fusion Panel is a combined DNA/RNA multi-cancer panel.
The assay combines the DNA-based oncoReveal Multi-Cancer v4 with CNV Panel with the oncoReveal
Multi-Cancer RNA Fusion v2 Panel allowing for joint sequencing. The assay uses proprietary Stem-Loop
Inhibition-Mediated amplification (SLIMamp®) technology, a tiled amplicon-based library prep chemistry for efficient single-tube target enrichment.
Gene:
ABL1 (ABL proto-oncogene 1), AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), ATM (ATM serine/threonine kinase), BRAF (B-raf proto-oncogene)
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ABL1 (ABL proto-oncogene 1), AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), ATM (ATM serine/threonine kinase), BRAF (B-raf proto-oncogene), CCNE1 (Cyclin E1), CDH1 (Cadherin 1), CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), CSF1R (Colony stimulating factor 1 receptor), CTNNB1 (Catenin (cadherin-associated protein), beta 1), DDR2 (Discoidin domain receptor 2), EGFR (Epidermal growth factor receptor), ERBB4 (erb-b2 receptor tyrosine kinase 4), EZH2 (Enhancer of zeste 2 polycomb repressive complex 2 subunit), FBXW7 (F-Box And WD Repeat Domain Containing 7), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), FLT3 (Fms-related tyrosine kinase 3), FOXL2 (Forkhead Box L2), GNA11 (G Protein Subunit Alpha 11), GNAQ (G Protein Subunit Alpha Q), GNAS (GNAS Complex Locus), HER-2 (Human epidermal growth factor receptor 2), HNF1A (HNF1 Homeobox A), HRAS (Harvey rat sarcoma viral oncogene homolog), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), JAK2 (Janus kinase 2), JAK3 (Janus Kinase 3), KDR (Kinase insert domain receptor), KIT (KIT proto-oncogene, receptor tyrosine kinase), KRAS (KRAS proto-oncogene GTPase), MAP2K1 (Mitogen-activated protein kinase kinase 1), MET (MET proto-oncogene, receptor tyrosine kinase), MLH1 (MutL homolog 1), MPL (MPL Proto-Oncogene, Thrombopoietin Receptor), MYC (V-myc avian myelocytomatosis viral oncogene homolog), NOTCH1 (Notch 1), NPM1 (Nucleophosmin 1), NRAS (Neuroblastoma RAS viral oncogene homolog), NTRK1 (Neurotrophic tyrosine kinase, receptor, type 1), NTRK2 (Neurotrophic tyrosine kinase, receptor, type 2), NTRK3 (Neurotrophic tyrosine kinase, receptor, type 3), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), PTEN (Phosphatase and tensin homolog), PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11), RAC1 (Rac Family Small GTPase 1), RB1 (RB Transcriptional Corepressor 1), RET (Ret Proto-Oncogene), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), SMAD4 (SMAD family member 4), SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1), SMO (Smoothened Frizzled Class Receptor), SRC (SRC Proto-Oncogene), STK11 (Serine/threonine kinase 11), TP53 (Tumor protein P53), VHL (von Hippel-Lindau tumor suppressor)
Method:
Next-Generation Sequencing (NGS)
