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our Premium Content: News alerts, weekly reports and conference plannersTEST:StrataNGS™ Test
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Company:
Strata OncologyType:
Laboratory Developed Test
Related tests:
The StrataNGS Test is a clinical assay performed in a CLIA-certified laboratory. It is a solid tumor, pan-cancer Next Generation Sequencing (NGS) test to detect mutations across 87 genes, copy number variations (amplifications and deep deletions) across
31 genes, and fusion events across 46 driver genes.
The assay utilizes the Ion S5 sequencing workflow, with libraries created using the StrataNGS Assay, incorporating Ampliseq chemistry. The assay runs up to 24 patient samples on one Ion 540 chip, utilizing both DNA and RNA from each sample.
Cancer:
Solid Tumor
Gene:
ALK (Anaplastic lymphoma kinase), ATM (ATM serine/threonine kinase), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), CDKN2A (Cyclin-dependent kinase inhibitor 2A), EGFR (Epidermal growth factor receptor)
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ALK (Anaplastic lymphoma kinase), ATM (ATM serine/threonine kinase), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), CDKN2A (Cyclin-dependent kinase inhibitor 2A), EGFR (Epidermal growth factor receptor), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), HER-2 (Human epidermal growth factor receptor 2), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), JAK1 (Janus Kinase 1), JAK2 (Janus kinase 2), JAK3 (Janus Kinase 3), KIT (KIT proto-oncogene, receptor tyrosine kinase), MET (MET proto-oncogene, receptor tyrosine kinase), MSH2 (MutS Homolog 2), MSH6 (MutS homolog 6), NTRK (Neurotrophic receptor tyrosine kinase), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), PTEN (Phosphatase and tensin homolog), RB1 (RB Transcriptional Corepressor 1), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), TERT (Telomerase Reverse Transcriptase), TP53 (Tumor protein P53)
Method:
Next-Generation Sequencing (NGS)
