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our Premium Content: News alerts, weekly reports and conference plannersTEST:NovoFocus™ CRC 2.0
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News alerts, weekly reports and conference planners
Company:
NovogeneType:
Laboratory Developed Test
Related tests:
NovoFocus™ CRC 2.0 Test is a next generation sequencing (NGS)-based assay that analyzes 50 genes related to Colorectal Cancer (CRC) for clinically important alterations at the DNA level and some other genes for Microsatellite Instability (MSI) status. It interrogates the complete coding region of 50 genes and introns of 10 genes. It can detect genomic abnormalities (SNV, InDel, CNV and Fusion) and MSI and provide targeted therapy/immunotherapy options.
Cancer:
Colorectal Cancer
Gene:
AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), BRAF (B-raf proto-oncogene), CCND1 (Cyclin D1), CDK4 (Cyclin-dependent kinase 4)
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AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), BRAF (B-raf proto-oncogene), CCND1 (Cyclin D1), CDK4 (Cyclin-dependent kinase 4), CDK6 (Cyclin-dependent kinase 6), DDR2 (Discoidin domain receptor 2), DPYD (Dihydropyrimidine Dehydrogenase), EGFR (Epidermal growth factor receptor), FBXW7 (F-Box And WD Repeat Domain Containing 7), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), GNA11 (G Protein Subunit Alpha 11), GNAQ (G Protein Subunit Alpha Q), HER-2 (Human epidermal growth factor receptor 2), HRAS (Harvey rat sarcoma viral oncogene homolog), JAK1 (Janus Kinase 1), JAK2 (Janus kinase 2), JAK3 (Janus Kinase 3), KIT (KIT proto-oncogene, receptor tyrosine kinase), KRAS (KRAS proto-oncogene GTPase), MAP2K1 (Mitogen-activated protein kinase kinase 1), MAP2K2 (Mitogen-activated protein kinase kinase 2), MET (MET proto-oncogene, receptor tyrosine kinase), MYC (V-myc avian myelocytomatosis viral oncogene homolog), NRAS (Neuroblastoma RAS viral oncogene homolog), NTRK1 (Neurotrophic tyrosine kinase, receptor, type 1), NTRK2 (Neurotrophic tyrosine kinase, receptor, type 2), NTRK3 (Neurotrophic tyrosine kinase, receptor, type 3), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), POLD1 (DNA Polymerase Delta 1), POLE (DNA Polymerase Epsilon), PTEN (Phosphatase and tensin homolog), RAF1 (Raf-1 Proto-Oncogene Serine/Threonine Kinase), RAI1 (Retinoic Acid Induced 1), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), TP53 (Tumor protein P53), TSC1 (TSC complex subunit 1), UGT1A1 (UDP glucuronosyltransferase family 1 member A1)
Method:
Next-Generation Sequencing (NGS)
