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our Premium Content: News alerts, weekly reports and conference plannersTEST:Archer® FusionPlex® Solid Tumor Kit
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News alerts, weekly reports and conference planners
Company:
Integrated DNA TechnologiesType:
Laboratory Developed Test
Related tests:
The Archer® FusionPlex® Solid Tumor Kit is a robust targeted sequencing assay to simultaneously detect and identify fusions and other mutations associated with over 50 genes linked to various carcinomas. This kit uses Archer’s proprietary Anchored Multiplex PCR (AMP™)-based enrichment to detect all fusions, even
without prior knowledge of fusion partners or breakpoints.
Cancer:
Solid Tumor
Gene:
AKT3 (V-akt murine thymoma viral oncogene homolog 3), ALK (Anaplastic lymphoma kinase), BRAF (B-raf proto-oncogene), EGFR (Epidermal growth factor receptor), ERG (ETS Transcription Factor ERG), ETV1 (ETS Variant Transcription Factor 1)
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AKT3 (V-akt murine thymoma viral oncogene homolog 3), ALK (Anaplastic lymphoma kinase), BRAF (B-raf proto-oncogene), EGFR (Epidermal growth factor receptor), ERG (ETS Transcription Factor ERG), ETV1 (ETS Variant Transcription Factor 1), ETV5 (ETS Variant Transcription Factor 5), ETV6 (ETS Variant Transcription Factor 6), EWSR1 (EWS RNA Binding Protein 1), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), MAML2 (Mastermind Like Transcriptional Coactivator 2), MET (MET proto-oncogene, receptor tyrosine kinase), MYB (MYB Proto-Oncogene, Transcription Factor), NOTCH1 (Notch 1), NOTCH2 (Notch 2), NRG1 (Neuregulin 1), NTRK1 (Neurotrophic tyrosine kinase, receptor, type 1), NTRK2 (Neurotrophic tyrosine kinase, receptor, type 2), NUTM1 (NUT Midline Carcinoma Family Member 1), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PDGFRB (Platelet Derived Growth Factor Receptor Beta), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), RET (Ret Proto-Oncogene), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), RSPO2 (R-Spondin 2), RSPO3 (R-Spondin 3), TERT (Telomerase Reverse Transcriptase), TFE3, TFEB (Transcription Factor EB 2), TMPRSS2 (Transmembrane serine protease 2)
Method:
Next-Generation Sequencing (NGS)
