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our Premium Content: News alerts, weekly reports and conference plannersTEST:FusionPlex® Pan Solid Tumor v2 panel
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Company:
Integrated DNA TechnologiesType:
Laboratory Developed Test
Related tests:
The FusionPlex Pan Solid Tumor v2 panel is a targeted next-generation sequencing (NGS) research product that expands on the FusionPlex Solid Tumor panel to include key fusions and variants relevant across solid tumors and sarcomas in 137 genes. This panel uses Anchored Multiplex PCR (AMP™)-based enrichment to detect all fusions associated with the genes in a single sequencing product, even without prior knowledge of fusion partners or breakpoints.
Cancer:
Solid Tumor
Gene:
AKT3 (V-akt murine thymoma viral oncogene homolog 3), ALK (Anaplastic lymphoma kinase), BRAF (B-raf proto-oncogene), EGFR (Epidermal growth factor receptor), ERG (ETS Transcription Factor ERG), ETV1 (ETS Variant Transcription Factor 1)
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AKT3 (V-akt murine thymoma viral oncogene homolog 3), ALK (Anaplastic lymphoma kinase), BRAF (B-raf proto-oncogene), EGFR (Epidermal growth factor receptor), ERG (ETS Transcription Factor ERG), ETV1 (ETS Variant Transcription Factor 1), ETV5 (ETS Variant Transcription Factor 5), ETV6 (ETS Variant Transcription Factor 6), EWSR1 (EWS RNA Binding Protein 1), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), MAML2 (Mastermind Like Transcriptional Coactivator 2), MET (MET proto-oncogene, receptor tyrosine kinase), MYB (MYB Proto-Oncogene, Transcription Factor), NOTCH1 (Notch 1), NOTCH2 (Notch 2), NRG1 (Neuregulin 1), NTRK1 (Neurotrophic tyrosine kinase, receptor, type 1), NTRK2 (Neurotrophic tyrosine kinase, receptor, type 2), NUTM1 (NUT Midline Carcinoma Family Member 1), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PDGFRB (Platelet Derived Growth Factor Receptor Beta), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), RET (Ret Proto-Oncogene), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), RSPO2 (R-Spondin 2), RSPO3 (R-Spondin 3), TERT (Telomerase Reverse Transcriptase), TFE3, TFEB (Transcription Factor EB 2), TMPRSS2 (Transmembrane serine protease 2)
Method:
Next-Generation Sequencing (NGS)
