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our Premium Content: News alerts, weekly reports and conference plannersTEST:NeoTYPE® Lung Tumor Profile
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News alerts, weekly reports and conference planners
Company:
NeoGenomicsType:
Laboratory Developed Test
Related tests:
The NeoTYPE Lung Tumor Profile analyzes 46 biomarkers through a combination of next-generation sequencing (NGS), other molecular methods, FISH, and IHC. The NeoTYPE Lung Tumor Profile characterizes primary or metastatic non-small cell tumors for the most significant genetic changes relevant to therapy decisions, prognosis, and clinical research. It is appropriate for patients with newly-diagnosed or recurrent disease, and for patients with resistant disease to explore options in clinical trials.
Cancer:
Lung Cancer
Gene:
AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), ARID1A (AT-rich interaction domain 1A), ATM (ATM serine/threonine kinase), ATR (Ataxia telangiectasia and Rad3-related protein), ATRX (ATRX Chromatin Remodeler)
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AKT1 (V-akt murine thymoma viral oncogene homolog 1), ALK (Anaplastic lymphoma kinase), ARID1A (AT-rich interaction domain 1A), ATM (ATM serine/threonine kinase), ATR (Ataxia telangiectasia and Rad3-related protein), ATRX (ATRX Chromatin Remodeler), BRAF (B-raf proto-oncogene), CCND1 (Cyclin D1), CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), CDKN2B (Cyclin Dependent Kinase Inhibitor 2B), EGFR (Epidermal growth factor receptor), ERBB4 (erb-b2 receptor tyrosine kinase 4), FBXW7 (F-Box And WD Repeat Domain Containing 7), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), HER-2 (Human epidermal growth factor receptor 2), KEAP1 (Kelch Like ECH Associated Protein 1), KIT (KIT proto-oncogene, receptor tyrosine kinase), KMT2D (Lysine Methyltransferase 2D), KRAS (KRAS proto-oncogene GTPase), MET (MET proto-oncogene, receptor tyrosine kinase), NF1 (Neurofibromin 1), NFE2L2 (Nuclear Factor, Erythroid 2 Like 2), NOTCH1 (Notch 1), NRAS (Neuroblastoma RAS viral oncogene homolog), PD-L1 (Programmed death ligand 1), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), PTEN (Phosphatase and tensin homolog), RB1 (RB Transcriptional Corepressor 1), RBM10 (RNA Binding Motif Protein 10), RET (Ret Proto-Oncogene), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), SMAD4 (SMAD family member 4), SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily A, member 4), SMO (Smoothened Frizzled Class Receptor), SRC (SRC Proto-Oncogene), STK11 (Serine/threonine kinase 11), TMB (Tumor Mutational Burden), TP53 (Tumor protein P53)
Method:
Next-Generation Sequencing (NGS) / Immunohistochemistry (IHC) / FISH
