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our Premium Content: News alerts, weekly reports and conference plannersTEST:oncoReveal™ Fusion LBx Panel
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Company:
Pillar BiosciType:
Laboratory Developed Test
Related tests:
The oncoReveal Fusion LBx panel is a robust NGS assay that interrogates multiple gene rearrangement regions of interest across multiple solid tumor cancer types. The assay uses proprietary Stem-Loop Inhibition-Mediated amplification (SLIMamp®) technology, a tiled amplicon-based library prep chemistry for efficient single-tube enrichment of targets from cell-free RNA extracted from plasma.
Cancer:
Solid Tumor
Gene:
ALK (Anaplastic lymphoma kinase), BRAF (B-raf proto-oncogene), EGFR (Epidermal growth factor receptor), ERG (ETS Transcription Factor ERG), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3)
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ALK (Anaplastic lymphoma kinase), BRAF (B-raf proto-oncogene), EGFR (Epidermal growth factor receptor), ERG (ETS Transcription Factor ERG), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), MET (MET proto-oncogene, receptor tyrosine kinase), NRG1 (Neuregulin 1), NTRK1 (Neurotrophic tyrosine kinase, receptor, type 1), NTRK2 (Neurotrophic tyrosine kinase, receptor, type 2), NTRK3 (Neurotrophic tyrosine kinase, receptor, type 3), PBX1 (PBX Homeobox 1), PPARG (Peroxisome Proliferator Activated Receptor Gamma), PRKACA (Protein Kinase CAMP-Activated Catalytic Subunit Alpha), RAF1 (Raf-1 Proto-Oncogene Serine/Threonine Kinase), RET (Ret Proto-Oncogene), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), TFE3 (Transcription Factor Binding To IGHM Enhancer 3)
Method:
Next-Generation Sequencing (NGS)
