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our Premium Content: News alerts, weekly reports and conference plannersTEST:GALEAS™ Hereditary Plus
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News alerts, weekly reports and conference planners
Company:
NonacusType:
Laboratory Developed Test
Related tests:
GALEAS HereditaryPlus is an innovative Next Generation Sequencing (NGS) panel that includes a meticulously curated collection of 146 genes well-established in their associations with hereditary cancer. The targeted gene list addresses not only key cancer syndromes like Lynch syndrome but also covers rarer hereditary cancer types like Phaeochromocytoma and pediatric cancers like Wilms tumor, ensuring a comprehensive understanding of the genetic landscape. The ability to target many types of cancer in one assay enables laboratories to streamline hereditary testing workflows.
Cancer:
Brain Cancer, Breast Cancer, Colon Cancer, Gastric Cancer, Gastrointestinal Stromal Tumor, Ovarian Cancer, Prostate Cancer, Renal Cell Carcinoma, Sarcoma, Wilms Tumor
Gene:
APC (APC Regulator Of WNT Signaling Pathway), ATM (ATM serine/threonine kinase), AXIN2 (Axin 2), BAP1 (BRCA1 Associated Protein 1), BARD1 (BRCA1 Associated RING Domain 1), BMPR1A (Bone Morphogenetic Protein Receptor Type 1A)
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APC (APC Regulator Of WNT Signaling Pathway), ATM (ATM serine/threonine kinase), AXIN2 (Axin 2), BAP1 (BRCA1 Associated Protein 1), BARD1 (BRCA1 Associated RING Domain 1), BMPR1A (Bone Morphogenetic Protein Receptor Type 1A), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), CDH1 (Cadherin 1), CDKN1C (Cyclin Dependent Kinase Inhibitor 1C), CHEK2 (Checkpoint kinase 2), EPCAM (Epithelial cell adhesion molecule), EXT1 (Exostosin Glycosyltransferase 1), EXT2 (Exostosin Glycosyltransferase 2), FH (Fumarate Hydratase), GREM1 (Gremlin 1), KIT (KIT proto-oncogene, receptor tyrosine kinase), MET (MET proto-oncogene, receptor tyrosine kinase), MLH1 (MutL homolog 1), MSH2 (MutS Homolog 2), MSH3 (MutS Homolog 3), MSH6 (MutS homolog 6), MTAP (Methylthioadenosine Phosphorylase), MUTYH (MutY homolog), NBN (Nibrin Nijmegen Breakage Syndrome 1 (Nibrin)), NF1 (Neurofibromin 1), PALB2 (Partner and localizer of BRCA2), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PMS2 (PMS1 protein homolog 2), POLD1 (DNA Polymerase Delta 1), POLE (DNA Polymerase Epsilon), PTEN (Phosphatase and tensin homolog), RAD51C (RAD51 paralog C), RAD51D (RAD51 paralog D), RECQL4( RecQ Like Helicase 4), RNF43 (Ring Finger Protein 43), SDHA (Succinate Dehydrogenase Complex Flavoprotein Subunit A), SDHB (Succinate Dehydrogenase Complex Iron Sulfur Subunit B), SDHC (Succinate Dehydrogenase Complex Subunit C), SDHD (Succinate Dehydrogenase Complex Subunit D), SMAD4 (SMAD family member 4), SQSTM1 (Sequestosome 1), STK11 (Serine/threonine kinase 11), TP53 (Tumor protein P53), TRIM28 (Tripartite Motif Containing 28), VHL (von Hippel-Lindau tumor suppressor), WT1 (WT1 Transcription Factor)
Method:
Next-Generation Sequencing (NGS)
