The CELsignia platform identifies patients with abnormal oncogenic signaling pathways to detect new treatment options for patients. CELsignia Test measures dynamic HER2, c-Met, and PI3K-node involved signaling activity in the living tumor cells of HER2-negative breast cancer patients. CELsignia tests provide pharmaceutical companies a new type of biomarker, dysregulated signaling activity, to identify additional patients eligible for their targeted therapies.