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BIOMARKER:

HER-2 amplification + RAS wild-type + BRAF wild-type

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Entrez ID:

Related biomarkers:

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BRAF V600E (255)

BRAF mutation (129)

BRAF V600 (106)

HER-2 mutation (89)

HER-2 exon 20 insertion (27)

HER-2 L755S (26)

BRAF V600K (25)

BRAF wild-type (25)

HER-2 A775_G776insYVMA (10)

HER-2 S310F (10)

HER-2 V777L (10)

HER-2 L755P (7)

RAS wild-type + BRAF wild-type (7)

HER-2 S310Y (6)

BRAF V600E + RNF43 mutation (6)

EGFR mutation + BRAF V600E (6)

HER-2 G778_P780dup (5)

HER-2 L768S (4)

HER-2 Y772_A775dup (4)

HER-2 exon 20 mutation (4)

BRAF V600E + PIK3CA mutation (4)

NRAS mutation + BRAF mutation (4)

HER-2 C634R (3)

HER-2 D769Y (3)

HER-2 I655V (3)

HER-2 K753E (3)

HER-2 L869R (3)

HER-2 V777L + EGFR L858R (3)

HER-2 V842I (3)

BRAF T1799A (3)

BRAF V600E + TERT mutation (3)

BRAF delNVTAP (3)

NRAS Q61K + BRAF V600E (3)

TERT mutation + BRAF V600E (3)

HER-2 G776insV_C (2)

HER-2 G776insV_G (2)

HER-2 G778_S779insCPG (2)

HER-2 G780_P781dupGSP (2)

HER-2 H878Y (2)

HER-2 L755_T759del (2)

HER-2 L866M (2)

HER-2 T798M (2)

HER-2 T862A + HER-2 L755S (2)

HER-2 V773A (2)

HER-2 V773L (2)

HER-2 V777L + PIK3CA H1047R (2)

HER-2 exon 20 YVMA insertion (2)

HER-2 exon 20G776>VC insertion (2)

BRAF V600E + MAP2K1 I111S (2)

BRAF mutation + MEK1 P124L (2)

BRAF mutation + NF1 mutation (2)

BRAF rearrangement (2)

EGFR mutation + BRAF V600 (2)

IDH1 wild-type + BRAF mutation (2)

KRAS G13D + BRAF mutation (2)

MYD88 L265P + BRAF V600E (2)

NRAS G12C + BRAF mutation (2)

ALK rearrangement + HER-2 mutation (1)

EGFR L858R + TP53 R273C + HER-2 S442L (1)

EGFR T790M + HER-2 mutation (1)

ERBB3 mutation + HER-2 mutation (1)

HER-2 1899‐1G>A (1)

HER-2 755_759del (1)

HER-2 778insGSP (1)

HER-2 A1170P (1)

HER-2 D769H (1)

HER-2 E395K (1)

HER-2 G309A (1)

HER-2 G660D + HER-2 S310F (1)

HER-2 G766V (1)

HER-2 G776L (1)

HER-2 G776S (1)

HER-2 K676R (1)

HER-2 L726I (1)

HER-2 M774delinsWLV (1)

HER-2 N857S (1)

HER-2 P780-Y781insGSP (1)

HER-2 P780ins (1)

HER-2 Q680R (1)

HER-2 R647K (1)

HER-2 R678Q (1)

HER-2 R784G (1)

HER-2 R896C (1)

HER-2 R896G (1)

HER-2 S335C (1)

HER-2 T798I (1)

HER-2 T862A (1)

HER-2 V658E (1)

HER-2 V659D (1)

HER-2 exon 17 mutation (1)

HER-2 exon 19 mutation (1)

HER-2 exon 20 G776delinsVC (1)

HER-2 exon 23 mutation (1)

HER-2 mutation + CDK6 mutation (1)

HER-2 mutation + HER-2 T798I (1)

HER-2 mutation + TP53 wild-type (1)

HER-2 rearrangement (1)

p95HER2 mutation (1)

AKT1 E17K + BRAF V600 (1)

BRAF 486_490 del (1)

BRAF G466E + NF1 Y2285fs*5 + NF1 Y2640fs*3 + TP53 D281Y (1)

BRAF G466V + KIT K509Q (1)

BRAF N486-P490del + TP53 V157G (1)

BRAF V600 wild-type (1)

BRAF V600DK601del (1)

BRAF V600E + BRAF G469A + BRAF G469V (1)

BRAF V600E + BRAF K601_W604del (1)

BRAF V600E + BRAF L514V (1)

BRAF V600E + BRAF V600K (1)

BRAF V600E + KRAS G12R (1)

BRAF V600E + MSI-H/dMMR (1)

BRAF V600E + TERT E441del + RET N579K + EZH2 D154E + CDK4 S259L (1)

BRAF V600_K601delinsE (1)

BRAF mutation + EGFR mutation (1)

BRAF mutation + MAP2K1 mutation (1)

BRAF mutation + RAS mutation (1)

BRAF mutation + TERT −124C>T (1)

BRAF mutation + TERT −138CC>TT (1)

BRAF mutation + TERT −139CC>TT (1)

BRAF mutation + TERT −146C>T (1)

BRAF mutation + TET2 mutation (1)

BRAF mutation + TP53 mutation (1)

BRAF wild-type + NRAS wild-type (1)

EGFR T790M + BRAF V600E (1)

EGFR exon 19 deletion + BRAF V600E (1)

EGFR mutation + BRAF G469A (1)

EGFR mutation + BRAF mutation + TP53 mutation (1)

KRAS G12A + BRAF D549N (1)

KRAS G12V + BRAF V600E (1)

MAP2K1 V211D + BRAF mutation (1)

NRAS G12C + BRAF V600E + BRAF V600D (1)

NRAS G13D + BRAF V600E (1)

RAS wild-type + BRAF wild-type + MAP2K1 N57K (1)

ROS1 rearrangement + BRAF V600E (1)

TERT promoter mutation + BRAF V600 (1)

HER-2 negative + HR positive + PTEN mutation (0)

HER-2 negative + ER positive + ESR1 mutation (0)

HER-2 negative + HR negative + BRCA mutation (0)

HER-2 negative + HR positive + AKT1 mutation (0)

HER-2 negative + HR positive + BRCA mutation (0)

HER-2 negative + HR positive + ESR1 mutation (0)

HER-2 negative + HR positive + ESR1 mutation + PIK3CA mutation (0)

HER-2 negative + HR positive + ESR1 wild-type (0)

HER-2 negative + HR positive + PIK3CA exon 20 mutation (0)

HER-2 negative + HR positive + PIK3CA exon 7 mutation (0)

HER-2 negative + HR positive + PIK3CA exon 9 mutation (0)

HER-2 negative + HR positive + PIK3CA mutation (0)

BRAF V600E + TERT mutation (0)

BRAF V600E + KRAS G12D (0)

BRAF V600E + MAP2K1 P124S (0)

BRAF exon 11 mutation (0)

BRAF exon 15 mutation (0)

CDKN2A mutation + BRAF V600E (0)

IDH mutation + BRAF V600E (0)

IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)

BRAF V600E (255)

BRAF mutation (129)

BRAF V600 (106)

HER-2 mutation (89)

HER-2 exon 20 insertion (27)

HER-2 L755S (26)

BRAF V600K (25)

BRAF wild-type (25)

HER-2 A775_G776insYVMA (10)

HER-2 S310F (10)

HER-2 V777L (10)

HER-2 L755P (7)

RAS wild-type + BRAF wild-type (7)

HER-2 S310Y (6)

BRAF V600E + RNF43 mutation (6)

EGFR mutation + BRAF V600E (6)

HER-2 G778_P780dup (5)

HER-2 L768S (4)

HER-2 Y772_A775dup (4)

HER-2 exon 20 mutation (4)

BRAF V600E + PIK3CA mutation (4)

NRAS mutation + BRAF mutation (4)

HER-2 C634R (3)

HER-2 D769Y (3)

HER-2 I655V (3)

HER-2 K753E (3)

HER-2 L869R (3)

HER-2 V777L + EGFR L858R (3)

HER-2 V842I (3)

BRAF T1799A (3)

BRAF V600E + TERT mutation (3)

BRAF delNVTAP (3)

NRAS Q61K + BRAF V600E (3)

TERT mutation + BRAF V600E (3)

HER-2 G776insV_C (2)

HER-2 G776insV_G (2)

HER-2 G778_S779insCPG (2)

HER-2 G780_P781dupGSP (2)

HER-2 H878Y (2)

HER-2 L755_T759del (2)

HER-2 L866M (2)

HER-2 T798M (2)

HER-2 T862A + HER-2 L755S (2)

HER-2 V773A (2)

HER-2 V773L (2)

HER-2 V777L + PIK3CA H1047R (2)

HER-2 exon 20 YVMA insertion (2)

HER-2 exon 20G776>VC insertion (2)

BRAF V600E + MAP2K1 I111S (2)

BRAF mutation + MEK1 P124L (2)

BRAF mutation + NF1 mutation (2)

BRAF rearrangement (2)

EGFR mutation + BRAF V600 (2)

IDH1 wild-type + BRAF mutation (2)

KRAS G13D + BRAF mutation (2)

MYD88 L265P + BRAF V600E (2)

NRAS G12C + BRAF mutation (2)

ALK rearrangement + HER-2 mutation (1)

EGFR L858R + TP53 R273C + HER-2 S442L (1)

EGFR T790M + HER-2 mutation (1)

ERBB3 mutation + HER-2 mutation (1)

HER-2 1899‐1G>A (1)

HER-2 755_759del (1)

HER-2 778insGSP (1)

HER-2 A1170P (1)

HER-2 D769H (1)

HER-2 E395K (1)

HER-2 G309A (1)

HER-2 G660D + HER-2 S310F (1)

HER-2 G766V (1)

HER-2 G776L (1)

HER-2 G776S (1)

HER-2 K676R (1)

HER-2 L726I (1)

HER-2 M774delinsWLV (1)

HER-2 N857S (1)

HER-2 P780-Y781insGSP (1)

HER-2 P780ins (1)

HER-2 Q680R (1)

HER-2 R647K (1)

HER-2 R678Q (1)

HER-2 R784G (1)

HER-2 R896C (1)

HER-2 R896G (1)

HER-2 S335C (1)

HER-2 T798I (1)

HER-2 T862A (1)

HER-2 V658E (1)

HER-2 V659D (1)

HER-2 exon 17 mutation (1)

HER-2 exon 19 mutation (1)

HER-2 exon 20 G776delinsVC (1)

HER-2 exon 23 mutation (1)

HER-2 mutation + CDK6 mutation (1)

HER-2 mutation + HER-2 T798I (1)

HER-2 mutation + TP53 wild-type (1)

HER-2 rearrangement (1)

p95HER2 mutation (1)

AKT1 E17K + BRAF V600 (1)

BRAF 486_490 del (1)

BRAF G466E + NF1 Y2285fs*5 + NF1 Y2640fs*3 + TP53 D281Y (1)

BRAF G466V + KIT K509Q (1)

BRAF N486-P490del + TP53 V157G (1)

BRAF V600 wild-type (1)

BRAF V600DK601del (1)

BRAF V600E + BRAF G469A + BRAF G469V (1)

BRAF V600E + BRAF K601_W604del (1)

BRAF V600E + BRAF L514V (1)

BRAF V600E + BRAF V600K (1)

BRAF V600E + KRAS G12R (1)

BRAF V600E + MSI-H/dMMR (1)

BRAF V600E + TERT E441del + RET N579K + EZH2 D154E + CDK4 S259L (1)

BRAF V600_K601delinsE (1)

BRAF mutation + EGFR mutation (1)

BRAF mutation + MAP2K1 mutation (1)

BRAF mutation + RAS mutation (1)

BRAF mutation + TERT −124C>T (1)

BRAF mutation + TERT −138CC>TT (1)

BRAF mutation + TERT −139CC>TT (1)

BRAF mutation + TERT −146C>T (1)

BRAF mutation + TET2 mutation (1)

BRAF mutation + TP53 mutation (1)

BRAF wild-type + NRAS wild-type (1)

EGFR T790M + BRAF V600E (1)

EGFR exon 19 deletion + BRAF V600E (1)

EGFR mutation + BRAF G469A (1)

EGFR mutation + BRAF mutation + TP53 mutation (1)

KRAS G12A + BRAF D549N (1)

KRAS G12V + BRAF V600E (1)

MAP2K1 V211D + BRAF mutation (1)

NRAS G12C + BRAF V600E + BRAF V600D (1)

NRAS G13D + BRAF V600E (1)

RAS wild-type + BRAF wild-type + MAP2K1 N57K (1)

ROS1 rearrangement + BRAF V600E (1)

TERT promoter mutation + BRAF V600 (1)

HER-2 negative + HR positive + PTEN mutation (0)

HER-2 negative + ER positive + ESR1 mutation (0)

HER-2 negative + HR negative + BRCA mutation (0)

HER-2 negative + HR positive + AKT1 mutation (0)

HER-2 negative + HR positive + BRCA mutation (0)

HER-2 negative + HR positive + ESR1 mutation (0)

HER-2 negative + HR positive + ESR1 mutation + PIK3CA mutation (0)

HER-2 negative + HR positive + ESR1 wild-type (0)

HER-2 negative + HR positive + PIK3CA exon 20 mutation (0)

HER-2 negative + HR positive + PIK3CA exon 7 mutation (0)

HER-2 negative + HR positive + PIK3CA exon 9 mutation (0)

HER-2 negative + HR positive + PIK3CA mutation (0)

BRAF V600E + TERT mutation (0)

BRAF V600E + KRAS G12D (0)

BRAF V600E + MAP2K1 P124S (0)

BRAF exon 11 mutation (0)

BRAF exon 15 mutation (0)

CDKN2A mutation + BRAF V600E (0)

IDH mutation + BRAF V600E (0)

IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)

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