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Association details:
Biomarker:
HER-2 amplification + RAS wild-type + BRAF wild-type
Cancer:
Rectal Cancer
Drug:
Enhertu (fam-trastuzumab deruxtecan-nxki)
(
Topoisomerase I inhibitor
,
HER2-targeted antibody-drug conjugate
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
Source:
NCCN
Published date:
01/25/2023
Excerpt:
Rectal cancer….Primary Treatment….Previous adjuvant FOLFOX/CAPEOX within past 12 mo…fam trastuzumab deruxtecan-nxki (HER2-amplified and RAS and BRAF WT)
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