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BIOMARKER:

HER-2 S310F

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Other names: ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
Entrez ID:
HER-2 S310F
Solid Tumor
BDTX-189
Sensitive: C2 – Inclusion Criteria
HER-2 S310F
LUAD
afatinib
Sensitive: C4 – Case Studies
HER-2 S310F
CRC
afatinib
Sensitive: C4 – Case Studies
HER-2 S310F
HER2 Negative Breast Cancer
lapatinib
Sensitive: C4 – Case Studies
HER-2 S310F
Gallbladder Cancer
lapatinib
Sensitive: C4 – Case Studies
HER-2 S310F
NSCLC
ado-trastuzumab emtansine
Sensitive: D – Preclinical
HER-2 S310F
CRC
cetuximab
Resistant: D – Preclinical
HER-2 S310F
CRC
panitumumab
Resistant: D – Preclinical