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BIOMARKER:

BRAF V600E + RNF43 mutation

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Other names: BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1, RNF43, Ring Finger Protein 43, RING-Type E3 Ubiquitin Transferase RNF43, E3 Ubiquitin-Protein Ligase RNF43, RING Finger Protein 43, EC 2.3.2.27, RNF124
Entrez ID:
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Trials
BRAF V600E + RNF43 mutation
CRC
cetuximab + encorafenib
Sensitive: C3 – Early Trials
BRAF V600E + RNF43 mutation
CRC
cetuximab + trametinib + dabrafenib
Sensitive: C3 – Early Trials
BRAF V600E + RNF43 mutation
CRC
cetuximab + trametinib + vemurafenib
Sensitive: C3 – Early Trials
BRAF V600E + RNF43 mutation
CRC
cetuximab + vemurafenib
Sensitive: C3 – Early Trials