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Association details:
Biomarker:
HER-2 amplification + RAS wild-type + BRAF wild-type
Cancer:
Colon Cancer
Drug:
Herceptin (trastuzumab)
(
HER2 inhibitor
) +
lapatinib
(
EGFR inhibitor
,
HER2 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
Colon cancer: Systemic therapy for advanced or metastatic disease…Trastuzumab + pertuzumab (HER2-amplified and RAS and BRAF WT)
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