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BIOMARKER:

HER-2 exon 20 insertion

i
Other names: ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
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Entrez ID:
HER-2 exon 20 insertion
Lung Adenocarcinoma
ado-trastuzumab emtansine
Sensitive
:
C3
Anticancer Drugs - 3 weeks - (New C4)
HER-2 exon 20 insertion
Solid Tumor
BDTX-189
Sensitive
:
B
HER-2 exon 20 insertion
Non Small Cell Lung Cancer
pyrotinib
Sensitive
:
C2
HER-2 exon 20 insertion
Non Small Cell Lung Cancer
poziotinib
Sensitive
:
C2
HER-2 exon 20 insertion
Non Small Cell Lung Cancer
DZD9008
Sensitive
:
C2
HER-2 exon 20 insertion
Non Small Cell Lung Cancer
dacomitinib
Sensitive
:
C3
HER-2 exon 20 insertion
Non Small Cell Lung Cancer
rivoceranib + pyrotinib
Sensitive
:
C3
HER-2 exon 20 insertion
Non Small Cell Lung Cancer
KN046
Sensitive
:
C3
HER-2 exon 20 insertion
Non Small Cell Lung Cancer
ado-trastuzumab emtansine
Sensitive
:
C3
HER-2 exon 20 insertion
HER2 Negative Breast Cancer
trastuzumab + neratinib
Sensitive
:
C3
HER-2 exon 20 insertion
Non Small Cell Lung Cancer
Immunotherapy
Resistant
:
C3
HER-2 exon 20 insertion
Non Small Cell Lung Cancer
durvalumab
Resistant
:
C3
HER-2 exon 20 insertion
Lung Adenocarcinoma
afatinib
Sensitive
:
C4
HER-2 exon 20 insertion
HER2 Positive Breast Cancer
neratinib + ado-trastuzumab emtansine
Sensitive
:
D
HER-2 exon 20 insertion
HER2 Positive Breast Cancer
neratinib + fam-trastuzumab deruxtecan-nxki
Sensitive
:
D
HER-2 exon 20 insertion
Lung Adenocarcinoma
poziotinib
Sensitive
:
D