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BIOMARKER:
BRAF wild-type
i
Other names:
BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1
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Entrez ID:
673
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
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BRAF wild-type
Cutaneous Melanoma
BRAF wild-type
Cutaneous Melanoma
nivolumab + ipilimumab
Sensitive: A2 - Guideline
nivolumab + ipilimumab
Sensitive
:
A2
nivolumab + ipilimumab
Sensitive: A2 - Guideline
nivolumab + ipilimumab
Sensitive
:
A2
BRAF wild-type
Cutaneous Melanoma
BRAF wild-type
Cutaneous Melanoma
pembrolizumab
Sensitive: A2 - Guideline
pembrolizumab
Sensitive
:
A2
pembrolizumab
Sensitive: A2 - Guideline
pembrolizumab
Sensitive
:
A2
BRAF wild-type
Cutaneous Melanoma
BRAF wild-type
Cutaneous Melanoma
nivolumab
Sensitive: A2 - Guideline
nivolumab
Sensitive
:
A2
nivolumab
Sensitive: A2 - Guideline
nivolumab
Sensitive
:
A2
BRAF wild-type
Colorectal Cancer
BRAF wild-type
Colorectal Cancer
cetuximab
Sensitive: A2 - Guideline
cetuximab
Sensitive
:
A2
cetuximab
Sensitive: A2 - Guideline
cetuximab
Sensitive
:
A2
BRAF wild-type
Colorectal Cancer
BRAF wild-type
Colorectal Cancer
panitumumab
Sensitive: A2 - Guideline
panitumumab
Sensitive
:
A2
panitumumab
Sensitive: A2 - Guideline
panitumumab
Sensitive
:
A2
BRAF wild-type
Colon Cancer
BRAF wild-type
Colon Cancer
cetuximab
Sensitive: A2 - Guideline
cetuximab
Sensitive
:
A2
cetuximab
Sensitive: A2 - Guideline
cetuximab
Sensitive
:
A2
BRAF wild-type
Colon Cancer
BRAF wild-type
Colon Cancer
panitumumab
Sensitive: A2 - Guideline
panitumumab
Sensitive
:
A2
panitumumab
Sensitive: A2 - Guideline
panitumumab
Sensitive
:
A2
BRAF wild-type
Rectal Cancer
BRAF wild-type
Rectal Cancer
cetuximab
Sensitive: A2 - Guideline
cetuximab
Sensitive
:
A2
cetuximab
Sensitive: A2 - Guideline
cetuximab
Sensitive
:
A2
BRAF wild-type
Rectal Cancer
BRAF wild-type
Rectal Cancer
panitumumab
Sensitive: A2 - Guideline
panitumumab
Sensitive
:
A2
panitumumab
Sensitive: A2 - Guideline
panitumumab
Sensitive
:
A2
BRAF wild-type
Melanoma
BRAF wild-type
Melanoma
nivolumab
Sensitive: B - Late Trials
nivolumab
Sensitive
:
B
nivolumab
Sensitive: B - Late Trials
nivolumab
Sensitive
:
B
BRAF wild-type
Colorectal Cancer
BRAF wild-type
Colorectal Cancer
bevacizumab
Sensitive: B - Late Trials
bevacizumab
Sensitive
:
B
bevacizumab
Sensitive: B - Late Trials
bevacizumab
Sensitive
:
B
BRAF wild-type
Melanoma
BRAF wild-type
Melanoma
selumetinib
Sensitive: C2 – Inclusion Criteria
selumetinib
Sensitive
:
C2
selumetinib
Sensitive: C2 – Inclusion Criteria
selumetinib
Sensitive
:
C2
BRAF wild-type
Melanoma
BRAF wild-type
Melanoma
trametinib
Sensitive: C2 – Inclusion Criteria
trametinib
Sensitive
:
C2
trametinib
Sensitive: C2 – Inclusion Criteria
trametinib
Sensitive
:
C2
BRAF wild-type
Colorectal Cancer
BRAF wild-type
Colorectal Cancer
anlotinib
Sensitive: C2 – Inclusion Criteria
anlotinib
Sensitive
:
C2
anlotinib
Sensitive: C2 – Inclusion Criteria
anlotinib
Sensitive
:
C2
BRAF wild-type
Colorectal Cancer
BRAF wild-type
Colorectal Cancer
CPGJ-602
Sensitive: C2 – Inclusion Criteria
CPGJ-602
Sensitive
:
C2
CPGJ-602
Sensitive: C2 – Inclusion Criteria
CPGJ-602
Sensitive
:
C2
BRAF wild-type
Colorectal Cancer
BRAF wild-type
Colorectal Cancer
SCT200
Sensitive: C2 – Inclusion Criteria
SCT200
Sensitive
:
C2
SCT200
Sensitive: C2 – Inclusion Criteria
SCT200
Sensitive
:
C2
BRAF wild-type
Colorectal Cancer
BRAF wild-type
Colorectal Cancer
cetuximab + avelumab
Sensitive: C2 – Inclusion Criteria
cetuximab + avelumab
Sensitive
:
C2
cetuximab + avelumab
Sensitive: C2 – Inclusion Criteria
cetuximab + avelumab
Sensitive
:
C2
BRAF wild-type
Melanoma
BRAF wild-type
Melanoma
pembrolizumab + trametinib
Sensitive: C3 – Early Trials
pembrolizumab + trametinib
Sensitive
:
C3
pembrolizumab + trametinib
Sensitive: C3 – Early Trials
pembrolizumab + trametinib
Sensitive
:
C3
BRAF wild-type
Melanoma
BRAF wild-type
Melanoma
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
BRAF wild-type
Colorectal Cancer
BRAF wild-type
Colorectal Cancer
EGFR inhibitor
Sensitive: C3 – Early Trials
EGFR inhibitor
Sensitive
:
C3
EGFR inhibitor
Sensitive: C3 – Early Trials
EGFR inhibitor
Sensitive
:
C3
BRAF wild-type
Non Small Cell Lung Cancer
BRAF wild-type
Non Small Cell Lung Cancer
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
BRAF wild-type
Ovarian Cancer
BRAF wild-type
Ovarian Cancer
olaparib
Sensitive: C3 – Early Trials
olaparib
Sensitive
:
C3
olaparib
Sensitive: C3 – Early Trials
olaparib
Sensitive
:
C3
BRAF wild-type
Glioblastoma
BRAF wild-type
Glioblastoma
panitumumab
Sensitive: C3 – Early Trials
panitumumab
Sensitive
:
C3
panitumumab
Sensitive: C3 – Early Trials
panitumumab
Sensitive
:
C3
BRAF wild-type
Melanoma
BRAF wild-type
Melanoma
dacarbazine
Sensitive: C4 – Case Studies
dacarbazine
Sensitive
:
C4
dacarbazine
Sensitive: C4 – Case Studies
dacarbazine
Sensitive
:
C4
BRAF wild-type
Cholangiocarcinoma
BRAF wild-type
Cholangiocarcinoma
lenvatinib
Sensitive: C4 – Case Studies
lenvatinib
Sensitive
:
C4
lenvatinib
Sensitive: C4 – Case Studies
lenvatinib
Sensitive
:
C4
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