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BIOMARKER:

HER-2 amplification + RAS wild-type + BRAF wild-type

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Other names: ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2, BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1
Entrez ID:
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Trials
HER-2 amplification + RAS wild-type + BRAF wild-type
Colon Cancer
trastuzumab + lapatinib
Sensitive: A2 - Guideline
HER-2 amplification + RAS wild-type + BRAF wild-type
Colon Cancer
trastuzumab + pertuzumab
Sensitive: A2 - Guideline
HER-2 amplification + RAS wild-type + BRAF wild-type
Rectal Cancer
trastuzumab + lapatinib
Sensitive: A2 - Guideline
HER-2 amplification + RAS wild-type + BRAF wild-type
Rectal Cancer
trastuzumab + pertuzumab
Sensitive: A2 - Guideline