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BIOMARKER:
BRAF K601E
i
Other names:
BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1
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Entrez ID:
673
Related biomarkers:
Mutation
CNA
Fusion
Others
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BRAF K601E
Melanoma
BRAF K601E
Melanoma
trametinib
Sensitive: C3 – Early Trials
AACR 2023 - 5 days (New D)
trametinib
Sensitive
:
C3
AACR 2023 - 5d
trametinib
Sensitive: C3 – Early Trials
AACR 2023 - 5 days
trametinib
Sensitive
:
C3
AACR 2023 - 5 days - (New D)
BRAF K601E
Melanoma
BRAF K601E
Melanoma
trametinib + sorafenib
Sensitive: D – Preclinical
AACR 2023 - 5 days (New D)
trametinib + sorafenib
Sensitive
:
D
AACR 2023 - 5d
trametinib + sorafenib
Sensitive: D – Preclinical
AACR 2023 - 5 days
trametinib + sorafenib
Sensitive
:
D
AACR 2023 - 5 days - (New D)
BRAF K601E
Melanoma
BRAF K601E
Melanoma
trametinib + dabrafenib
Sensitive: D – Preclinical
AACR 2023 - 5 days (New D)
trametinib + dabrafenib
Sensitive
:
D
AACR 2023 - 5d
trametinib + dabrafenib
Sensitive: D – Preclinical
AACR 2023 - 5 days
trametinib + dabrafenib
Sensitive
:
D
AACR 2023 - 5 days - (New D)
BRAF K601E
Melanoma
BRAF K601E
Melanoma
vemurafenib
Resistant: C4 – Case Studies
vemurafenib
Resistant
:
C4
vemurafenib
Resistant: C4 – Case Studies
vemurafenib
Resistant
:
C4
BRAF K601E
Melanoma
BRAF K601E
Melanoma
sorafenib
Sensitive: D – Preclinical
sorafenib
Sensitive
:
D
sorafenib
Sensitive: D – Preclinical
sorafenib
Sensitive
:
D
BRAF K601E
Melanoma
BRAF K601E
Melanoma
U0126
Sensitive: D – Preclinical
U0126
Sensitive
:
D
U0126
Sensitive: D – Preclinical
U0126
Sensitive
:
D
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