^
    BIOMARKER:

    BRAF V600E + PIK3CA mutation

    i
    Other names: BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1, PIK3CA, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha, Phosphoinositide-3-kinase, catalytic, alpha polypeptide,
    Entrez ID:
    673; 5290
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others

    Associations

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    Trials
    BRAF V600E + PIK3CA mutation
    CRC
    cetuximab + alpelisib + encorafenib
    Resistant: C3 – Early Trials
    BRAF V600E + PIK3CA mutation
    CRC
    cetuximab + binimetinib + encorafenib
    Resistant: C3 – Early Trials
    BRAF V600E + PIK3CA mutation
    CRC
    cetuximab + encorafenib
    Resistant: C3 – Early Trials
    BRAF V600E + PIK3CA mutation
    Astrocytoma
    vemurafenib + everolimus
    Sensitive: C4 – Case Studies