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BIOMARKER:
HER-2 V777L
i
Other names:
ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
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Entrez ID:
2064
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
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HER-2 V777L
HER2 Negative Breast Cancer
HER-2 V777L
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 V777L
Breast Cancer
HER-2 V777L
Breast Cancer
trastuzumab
Resistant: C3 – Early Trials
trastuzumab
Resistant
:
C3
trastuzumab
Resistant: C3 – Early Trials
trastuzumab
Resistant
:
C3
HER-2 V777L
HER2 Negative Breast Cancer
HER-2 V777L
HER2 Negative Breast Cancer
trastuzumab + neratinib
Sensitive: C3 – Early Trials
trastuzumab + neratinib
Sensitive
:
C3
trastuzumab + neratinib
Sensitive: C3 – Early Trials
trastuzumab + neratinib
Sensitive
:
C3
HER-2 V777L
Gastric Cancer
HER-2 V777L
Gastric Cancer
tucatinib
Sensitive: D – Preclinical
tucatinib
Sensitive
:
D
tucatinib
Sensitive: D – Preclinical
tucatinib
Sensitive
:
D
HER-2 V777L
Breast Cancer
HER-2 V777L
Breast Cancer
ado-trastuzumab emtansine
Resistant: D – Preclinical
ado-trastuzumab emtansine
Resistant
:
D
ado-trastuzumab emtansine
Resistant: D – Preclinical
ado-trastuzumab emtansine
Resistant
:
D
HER-2 V777L
Colorectal Cancer
HER-2 V777L
Colorectal Cancer
trastuzumab + tucatinib
Sensitive: D – Preclinical
trastuzumab + tucatinib
Sensitive
:
D
trastuzumab + tucatinib
Sensitive: D – Preclinical
trastuzumab + tucatinib
Sensitive
:
D
HER-2 V777L
Colorectal Cancer
HER-2 V777L
Colorectal Cancer
tucatinib
Sensitive: D – Preclinical
tucatinib
Sensitive
:
D
tucatinib
Sensitive: D – Preclinical
tucatinib
Sensitive
:
D
HER-2 V777L
Non Small Cell Lung Cancer
HER-2 V777L
Non Small Cell Lung Cancer
tucatinib
Sensitive: D – Preclinical
tucatinib
Sensitive
:
D
tucatinib
Sensitive: D – Preclinical
tucatinib
Sensitive
:
D
HER-2 V777L
Colorectal Cancer
HER-2 V777L
Colorectal Cancer
cetuximab
Resistant: D – Preclinical
cetuximab
Resistant
:
D
cetuximab
Resistant: D – Preclinical
cetuximab
Resistant
:
D
HER-2 V777L
Colorectal Cancer
HER-2 V777L
Colorectal Cancer
panitumumab
Resistant: D – Preclinical
panitumumab
Resistant
:
D
panitumumab
Resistant: D – Preclinical
panitumumab
Resistant
:
D
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