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GENE:
FLT3 (Fms-related tyrosine kinase 3)
i
Other names:
FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
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Entrez ID:
2322
Related tests:
‹
FoundationOne® Heme CDx (10)
LeukoStrat® CDx FLT3 Mutation Assay (6)
TruSeq®Amplicon - Cancer Panel (5)
Oncomine™ Pan-Cancer Cell-Free Assay (4)
Oncomine™ Comprehensive Assay v3M (2)
UW-Oncoplex™ (2)
AML Express™
AVENIO Tumor Tissue CGP Kit
AVENIO Tumor Tissue Expanded Kit
AVENIO ctDNA Expanded Kit
Archer® FusionPlex® Acute Lymphoblastic Leukemia (ALL)
Archer® FusionPlex® Myeloid Kit
Archer® VariantPlex® Myeloid panel
Archer® VariantPlex® Solid Tumor Kit
Archer™ VARIANTPlex™ Pan Solid Tumor panel
FLT3 ITD MRD Assay
FusionPlex™ Pan-Heme panel
LiquidHALLMARK®
MRDaccuPanel™ AML FLT3-ITD
Neo Comprehensive™ - Heme Cancers
NeoLAB® Solid Tumor Liquid Biopsy
OncoGuide™ NCC Oncopanel System
OncoSTRAT&GO
Oncomine Myeloid Assay GX
Oncomine Precision Assay
Oncomine Tumor Mutation Load Assay
Oncomine™ Myeloid MRD Assays
SOPHiA DDM™ Myeloid Solution
SOPHiA Myeloid Plus Solution
SafeSEQ AML MRD Assay
SureSeq™ Myeloid MRD Panel
SureSeq™ Myeloid Plus Panel
SureSeq™ Pan-Myeloid Panel
Tempus xF Assay
Tempus xO assay
TruSight Myeloid Sequencing Panel
TruSight Tumor 170 Assay
VarMap™ Pan-Cancer NGS Panel
Vartrace® AML Panel
oncoReveal™ Multi-Cancer with CNV & RNA Fusion Panel
FoundationOne® Heme CDx (10)
LeukoStrat® CDx FLT3 Mutation Assay (6)
TruSeq®Amplicon - Cancer Panel (5)
Oncomine™ Pan-Cancer Cell-Free Assay (4)
Oncomine™ Comprehensive Assay v3M (2)
UW-Oncoplex™ (2)
AML Express™
AVENIO Tumor Tissue CGP Kit
AVENIO Tumor Tissue Expanded Kit
AVENIO ctDNA Expanded Kit
Archer® FusionPlex® Acute Lymphoblastic Leukemia (ALL)
Archer® FusionPlex® Myeloid Kit
Archer® VariantPlex® Myeloid panel
Archer® VariantPlex® Solid Tumor Kit
Archer™ VARIANTPlex™ Pan Solid Tumor panel
FLT3 ITD MRD Assay
FusionPlex™ Pan-Heme panel
LiquidHALLMARK®
MRDaccuPanel™ AML FLT3-ITD
Neo Comprehensive™ - Heme Cancers
NeoLAB® Solid Tumor Liquid Biopsy
OncoGuide™ NCC Oncopanel System
OncoSTRAT&GO
Oncomine Myeloid Assay GX
Oncomine Precision Assay
Oncomine Tumor Mutation Load Assay
Oncomine™ Myeloid MRD Assays
SOPHiA DDM™ Myeloid Solution
SOPHiA Myeloid Plus Solution
SafeSEQ AML MRD Assay
SureSeq™ Myeloid MRD Panel
SureSeq™ Myeloid Plus Panel
SureSeq™ Pan-Myeloid Panel
Tempus xF Assay
Tempus xO assay
TruSight Myeloid Sequencing Panel
TruSight Tumor 170 Assay
VarMap™ Pan-Cancer NGS Panel
Vartrace® AML Panel
oncoReveal™ Multi-Cancer with CNV & RNA Fusion Panel
›
Associations
(362)
News
Trials
VERI cancer hierarchy
Reset Filters
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive: A1 - Approval
gilteritinib
Sensitive
:
A1
gilteritinib
Sensitive: A1 - Approval
gilteritinib
Sensitive
:
A1
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
midostaurin
Sensitive: A1 - Approval
midostaurin
Sensitive
:
A1
midostaurin
Sensitive: A1 - Approval
midostaurin
Sensitive
:
A1
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
quizartinib
Sensitive: A1 - Approval
quizartinib
Sensitive
:
A1
quizartinib
Sensitive: A1 - Approval
quizartinib
Sensitive
:
A1
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
midostaurin
Sensitive: A2 - Guideline
midostaurin
Sensitive
:
A2
midostaurin
Sensitive: A2 - Guideline
midostaurin
Sensitive
:
A2
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
midostaurin
Sensitive: A2 - Guideline
midostaurin
Sensitive
:
A2
midostaurin
Sensitive: A2 - Guideline
midostaurin
Sensitive
:
A2
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive: A2 - Guideline
gilteritinib
Sensitive
:
A2
gilteritinib
Sensitive: A2 - Guideline
gilteritinib
Sensitive
:
A2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
venetoclax
Sensitive: A2 - Guideline
venetoclax
Sensitive
:
A2
venetoclax
Sensitive: A2 - Guideline
venetoclax
Sensitive
:
A2
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
sorafenib
Sensitive: A2 - Guideline
sorafenib
Sensitive
:
A2
sorafenib
Sensitive: A2 - Guideline
sorafenib
Sensitive
:
A2
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive: A2 - Guideline
gilteritinib
Sensitive
:
A2
gilteritinib
Sensitive: A2 - Guideline
gilteritinib
Sensitive
:
A2
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
cytarabine + midostaurin + daunorubicin
Sensitive: A2 - Guideline
cytarabine + midostaurin + daunorubicin
Sensitive
:
A2
cytarabine + midostaurin + daunorubicin
Sensitive: A2 - Guideline
cytarabine + midostaurin + daunorubicin
Sensitive
:
A2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
gemtuzumab ozogamicin
Sensitive: A2 - Guideline
gemtuzumab ozogamicin
Sensitive
:
A2
gemtuzumab ozogamicin
Sensitive: A2 - Guideline
gemtuzumab ozogamicin
Sensitive
:
A2
FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
cytarabine
Resistant: B - Late Trials
cytarabine
Resistant
:
B
cytarabine
Resistant: B - Late Trials
cytarabine
Resistant
:
B
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
venetoclax
Sensitive: B - Late Trials
venetoclax
Sensitive
:
B
venetoclax
Sensitive: B - Late Trials
venetoclax
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 inhibitor
Sensitive: B - Late Trials
FLT3 inhibitor
Sensitive
:
B
FLT3 inhibitor
Sensitive: B - Late Trials
FLT3 inhibitor
Sensitive
:
B
FLT3‐ITD + WT1 mutation
Acute Myelogenous Leukemia
FLT3‐ITD + WT1 mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
FLT3‐ITD + NPM1 mutation
Acute Myelogenous Leukemia
FLT3‐ITD + NPM1 mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
FLT3‐ITD mutation + DNMT3A mutation + NPM1 mutation
Acute Myelogenous Leukemia
FLT3‐ITD mutation + DNMT3A mutation + NPM1 mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
FLT3‐ITD + DNMT3A mutation
Acute Myelogenous Leukemia
FLT3‐ITD + DNMT3A mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
FLT3‐ITD
Acute Myelogenous Leukemia
FLT3‐ITD
Acute Myelogenous Leukemia
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
venetoclax + azacitidine
Sensitive: B - Late Trials
venetoclax + azacitidine
Sensitive
:
B
venetoclax + azacitidine
Sensitive: B - Late Trials
venetoclax + azacitidine
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
venetoclax + azacitidine
Sensitive: B - Late Trials
venetoclax + azacitidine
Sensitive
:
B
venetoclax + azacitidine
Sensitive: B - Late Trials
venetoclax + azacitidine
Sensitive
:
B
FLT3 mutation
Leukemia
FLT3 mutation
Leukemia
midostaurin
Sensitive: B - Late Trials
midostaurin
Sensitive
:
B
midostaurin
Sensitive: B - Late Trials
midostaurin
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
azacitidine
Sensitive: B - Late Trials
azacitidine
Sensitive
:
B
azacitidine
Sensitive: B - Late Trials
azacitidine
Sensitive
:
B
FLT3 wild-type
Acute Myelogenous Leukemia
FLT3 wild-type
Acute Myelogenous Leukemia
venetoclax
Sensitive: B - Late Trials
venetoclax
Sensitive
:
B
venetoclax
Sensitive: B - Late Trials
venetoclax
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
HM43239
Sensitive: B - Late Trials
HM43239
Sensitive
:
B
HM43239
Sensitive: B - Late Trials
HM43239
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
quizartinib + RAIN-32
Sensitive: C2 – Inclusion Criteria
quizartinib + RAIN-32
Sensitive
:
C2
quizartinib + RAIN-32
Sensitive: C2 – Inclusion Criteria
quizartinib + RAIN-32
Sensitive
:
C2
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
ponatinib
Sensitive: C2 – Inclusion Criteria
ponatinib
Sensitive
:
C2
ponatinib
Sensitive: C2 – Inclusion Criteria
ponatinib
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
sunitinib
Sensitive: C2 – Inclusion Criteria
sunitinib
Sensitive
:
C2
sunitinib
Sensitive: C2 – Inclusion Criteria
sunitinib
Sensitive
:
C2
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
TP-0903
Sensitive: C2 – Inclusion Criteria
TP-0903
Sensitive
:
C2
TP-0903
Sensitive: C2 – Inclusion Criteria
TP-0903
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
quizartinib
Sensitive: C2 – Inclusion Criteria
quizartinib
Sensitive
:
C2
quizartinib
Sensitive: C2 – Inclusion Criteria
quizartinib
Sensitive
:
C2
^
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