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our Premium Content: News alerts, weekly reports and conference plannersTEST:Archer® VariantPlex® Myeloid panel
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News alerts, weekly reports and conference planners
Company:
Integrated DNA TechnologiesType:
Laboratory Developed Test
Related tests:
The Archer® VariantPlex® Myeloid panel is a 75-gene targeted sequencing panel for AML, MPN, MDS and some Lymphoid malignancy markers. Powered by Anchored Multiplex PCR (AMP™) chemistry, this panel enables deep strand-specific amplification of molecular barcoded DNA fragments for sequencing. Archer® VariantPlex® kits are designed for the study of target genes from DNA extracted from several types of samples, and allow the detection of SNVs, indels and CNVs by means of the Archer Analysis software for the analysis and interpretation of the data.
Cancer:
Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm
Gene:
ABL1 (ABL proto-oncogene 1), ASXL1 (ASXL Transcriptional Regulator 1), ATRX (ATRX Chromatin Remodeler), BCOR (BCL6 Corepressor), BRAF (B-raf proto-oncogene), CALR (Calreticulin)
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ABL1 (ABL proto-oncogene 1), ASXL1 (ASXL Transcriptional Regulator 1), ATRX (ATRX Chromatin Remodeler), BCOR (BCL6 Corepressor), BRAF (B-raf proto-oncogene), CALR (Calreticulin), CBL (Cbl proto-oncogene), CCND2 (Cyclin D2), CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), CEBPA (CCAAT Enhancer Binding Protein Alpha), CSF3R (Colony Stimulating Factor 3 Receptor), CUX1 (cut like homeobox 1), CXCR4 (Chemokine (C-X-C motif) receptor 4), DNMT3A (DNA methyltransferase 1), ETV6 (ETS Variant Transcription Factor 6), EZH2 (Enhancer of zeste 2 polycomb repressive complex 2 subunit), FBXW7 (F-Box And WD Repeat Domain Containing 7), FLT3 (Fms-related tyrosine kinase 3), GATA1 (GATA Binding Protein 1), GATA2 (GATA Binding Protein 2), GNAS (GNAS Complex Locus), HRAS (Harvey rat sarcoma viral oncogene homolog), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), IKZF1 (IKAROS Family Zinc Finger 1), JAK2 (Janus kinase 2), JAK3 (Janus Kinase 3), KDM6A (Lysine Demethylase 6A), KIT (KIT proto-oncogene, receptor tyrosine kinase), KMT2A (Lysine Methyltransferase 2A), KRAS (KRAS proto-oncogene GTPase), MAP2K1 (Mitogen-activated protein kinase kinase 1), MYC (V-myc avian myelocytomatosis viral oncogene homolog), MYD88 (MYD88 Innate Immune Signal Transduction Adaptor), NF1 (Neurofibromin 1), NOTCH1 (Notch 1), NPM1 (Nucleophosmin 1), NRAS (Neuroblastoma RAS viral oncogene homolog), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PHF6 (PHD Finger Protein 6), PPM1D (Protein Phosphatase Mg2+/Mn2+ Dependent 1D), PTEN (Phosphatase and tensin homolog), PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11), RAD21 (RAD21 Cohesin Complex Component), RUNX1 (RUNX Family Transcription Factor 1), SETBP1 (SET Binding Protein 1), SF3B1 (Splicing Factor 3b Subunit 1), SRSF2 (Serine and arginine rich splicing factor 2), STAG3 (Stromal Antigen 3), STAT3 (Signal Transducer And Activator Of Transcription 3), TP53 (Tumor protein P53), WT1 (WT1 Transcription Factor), XPO1 (Exportin 1)
Method:
Next-Generation Sequencing (NGS)
