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our Premium Content: News alerts, weekly reports and conference plannersTEST:Archer® FusionPlex® Acute Lymphoblastic Leukemia (ALL)
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News alerts, weekly reports and conference planners
Company:
Integrated DNA TechnologiesType:
Laboratory Developed Test
Related tests:
The Archer® FusionPlex® Acute Lymphoblastic Leukemia (ALL) Kit is a targeted next-generation sequencing assay to detect and identify fusions, point mutations and expression levels in 81 genes associated with Acute Lymphoblastic Leukemia, including recurrent Ph-Like ALL fusion events. The kit uses Archer’s proprietary Anchored Multiplex PCR (AMP™)-based enrichment to detect fusions, even without prior knowledge of fusion partners or breakpoints.
Cancer:
Acute Lymphocytic Leukemia
Gene:
ABL1 (ABL proto-oncogene 1), ABL2 (ABL Proto-Oncogene 2, Non-Receptor Tyrosine Kinase), BCL11B (BAF Chromatin Remodeling Complex Subunit BCL11B), BCL2 (B-cell CLL/lymphoma 2), BCL6 (B-cell CLL/lymphoma 6), BRAF (B-raf proto-oncogene)
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ABL1 (ABL proto-oncogene 1), ABL2 (ABL Proto-Oncogene 2, Non-Receptor Tyrosine Kinase), BCL11B (BAF Chromatin Remodeling Complex Subunit BCL11B), BCL2 (B-cell CLL/lymphoma 2), BCL6 (B-cell CLL/lymphoma 6), BRAF (B-raf proto-oncogene), FLT3 (Fms-related tyrosine kinase 3), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IKZF1 (IKAROS Family Zinc Finger 1), IKZF2 (IKAROS family zinc finger 2), IKZF3 (IKAROS Family Zinc Finger 3), JAK1 (Janus Kinase 1), JAK2 (Janus kinase 2), KRAS (KRAS proto-oncogene GTPase), MYC (V-myc avian myelocytomatosis viral oncogene homolog), NOTCH1 (Notch 1), NRAS (Neuroblastoma RAS viral oncogene homolog), PD-L1 (Programmed death ligand 1)
Method:
Next-Generation Sequencing (NGS)
