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our Premium Content: News alerts, weekly reports and conference plannersTEST:AVENIO Tumor Tissue Expanded Kit
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News alerts, weekly reports and conference planners
Company:
RocheType:
Laboratory Developed Test
Related tests:
The AVENIO Tumor Tissue Expanded Kit is an NGS assay for expanded profiling of solid tumors in formalin-fixed paraffin-embedded (FFPE) tissue samples. This assay contains 77 genes. It features all four mutation classes (SNVs, indels, fusions and CNVs) in a single DNA workflow with exceptional sensitivity and specificity. It has 99% success rate for FFPE tissue samples that pass input QC testing using the AVENIO QC kit included with the assay.
Cancer:
Solid Tumor
Gene:
ABL1 (ABL proto-oncogene 1), AKT1 (V-akt murine thymoma viral oncogene homolog 1), AKT2 (V-akt murine thymoma viral oncogene homolog 2), BRAF (B-raf proto-oncogene), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset)
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ABL1 (ABL proto-oncogene 1), AKT1 (V-akt murine thymoma viral oncogene homolog 1), AKT2 (V-akt murine thymoma viral oncogene homolog 2), BRAF (B-raf proto-oncogene), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), CCND1 (Cyclin D1), CCND2 (Cyclin D2), CCND3 (Cyclin D3), CDK4 (Cyclin-dependent kinase 4), ER (Estrogen receptor), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), FLT1 (Fms-related tyrosine kinase 1), FLT3 (Fms-related tyrosine kinase 3), FLT4 (Fms-related tyrosine kinase 4), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), JAK2 (Janus kinase 2), JAK3 (Janus Kinase 3), KRAS (KRAS proto-oncogene GTPase), NRAS (Neuroblastoma RAS viral oncogene homolog), NTRK1 (Neurotrophic tyrosine kinase, receptor, type 1), PD-L1 (Programmed death ligand 1), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PDGFRB (Platelet Derived Growth Factor Receptor Beta), PTCH1 (Patched 1), PTEN (Phosphatase and tensin homolog), RET (Ret Proto-Oncogene), SMO (Smoothened Frizzled Class Receptor), TP53 (Tumor protein P53)
Method:
Next-Generation Sequencing (NGS)
