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TEST:
SureSeq™ Pan-Myeloid Panel

Company:
Sysmex Corp
Type:
Laboratory Developed Test
Related tests:

Details

Evidence
The SureSeq™ Pan-Myeloid Panel has been designed with input from recognised cancer experts to detect key variants in 70 genes implicated in a wide range of myeloid disorders, including acute myeloid leukaemia (AML), myeloproliferative neoplasms (MPNs) and myelodysplastic syndrome (MDS). The SureSeq Pan-Myeloid Panel accurately detects SNVs and indels in genes such as CEBPA, JAK2, CALR and MPL, as well as structural variants including FLT3-ITDs and KMT2A-PTDs, providing researchers with a single NGS workflow delivering a comprehensive picture of the genetic make-up of each myeloid sample.
Cancer:
Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm
Gene:
ABL1 (ABL proto-oncogene 1), ASXL1 (ASXL Transcriptional Regulator 1), BCOR (BCL6 Corepressor), BCORL1 (BCL6 Corepressor Like 1), BIRC3 (Baculoviral IAP repeat containing 3), BRAF (B-raf proto-oncogene)
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Method:
Next-Generation Sequencing (NGS)