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our Premium Content: News alerts, weekly reports and conference plannersTEST:AVENIO ctDNA Expanded Kit
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News alerts, weekly reports and conference planners
Company:
RocheType:
Laboratory Developed Test
Related tests:
The AVENIO ctDNA Expanded Kit is a next-generation sequencing (NGS) liquid biopsy assay with a 77 gene panel and emerging cancer biomarkers. The Expanded Kit is a pan-cancer assay that’s specially optimized for lung cancer and colorectal cancer (CRC). Accurate detection of all four classes of mutations with high sensitivity and specificity: >99% sensitivity for all four classes of mutations; >99% positive predictive value (PPV) for indels, fusions and CNVs, and >98% PPV for SNVs.
Cancer:
Colorectal Cancer, Lung Cancer
Gene:
ABL1 (ABL proto-oncogene 1), AKT1 (V-akt murine thymoma viral oncogene homolog 1), BRAF (B-raf proto-oncogene), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), DPYD (Dihydropyrimidine Dehydrogenase)
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ABL1 (ABL proto-oncogene 1), AKT1 (V-akt murine thymoma viral oncogene homolog 1), BRAF (B-raf proto-oncogene), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), DPYD (Dihydropyrimidine Dehydrogenase), EGFR (Epidermal growth factor receptor), ER (Estrogen receptor), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), FLT1 (Fms-related tyrosine kinase 1), FLT3 (Fms-related tyrosine kinase 3), FLT4 (Fms-related tyrosine kinase 4), GNAS (GNAS Complex Locus), HER-2 (Human epidermal growth factor receptor 2), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), JAK2 (Janus kinase 2), JAK3 (Janus Kinase 3), KDR (Kinase insert domain receptor), KIT (KIT proto-oncogene, receptor tyrosine kinase), KRAS (KRAS proto-oncogene GTPase), NRAS (Neuroblastoma RAS viral oncogene homolog), PD-L1 (Programmed death ligand 1), PTCH1 (Patched 1), PTEN (Phosphatase and tensin homolog), RET (Ret Proto-Oncogene), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), SMO (Smoothened Frizzled Class Receptor), TP53 (Tumor protein P53)
Method:
Next-Generation Sequencing (NGS)
