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Tempus xF Assay

Laboratory Developed Test
Related tests:
Tempus xF, a liquid biopsy cell-free DNA assay that analyzes 77 genes, to its sequencing capabilities. Its is a non-invasive genomic sequencing panel. The assay is capable of detecting mutations in two variant classes in ~105 genes, including: Single Nucleotide Variants (SNVs) and insertions and deletions (indels), as well as Copy Number Amplifications (CNAs) in 6 genes, Copy Number Deletions (CNDs) in 2 genes,* and gene rearrangements (translocations) in 7 genes spanning ~0.3 Mb of genomic space. Microsatellite Instability High (MSI-H) status is also reported when detected. The panel is designed to provide clinical decision support for patients with solid tumors and is focused on the identification of oncologic, including resistance, mutations.
Solid Tumor
AKT1 (V-akt murine thymoma viral oncogene homolog 1), AKT2 (V-akt murine thymoma viral oncogene homolog 2), ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), AR (Androgen receptor), ARAF (A-Raf Proto-Oncogene)
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Next-Generation Sequencing (NGS)