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our Premium Content: News alerts, weekly reports and conference plannersTEST:Oncomine™ Myeloid MRD Assays
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News alerts, weekly reports and conference planners
Company:
Thermo Fisher ScientificType:
Laboratory Developed Test
Related tests:
The new Ion Torrent™ Oncomine™ Myeloid MRD Assays (RUO) on the Ion GeneStudio™ S5 System offer a complete NGS solution for myeloid MRD detection. A DNA and an RNA assay are available to cover a wide range of myeloid MRD targets, including key single-nucleotide variants (SNVs), insertions and deletions (indels), tandem duplications, and key gene fusions. Detect important biomarkers like NPM1, PML-RARA,
IDH1/2, BCR-ABL1, and FLT3 (ITD and TKD). The carefully curated targets on the panel are relevant for all major types of myeloid neoplasms, including acute myeloid leukemias (AML), myelodysplastic syndromes (MDS), and myeloproliferative neoplasms (MPN) samples.
Cancer:
Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm
Gene:
ABL1 (ABL proto-oncogene 1), ASXL1 (ASXL Transcriptional Regulator 1), BCOR (BCL6 Corepressor), BRAF (B-raf proto-oncogene), CEBPA (CCAAT Enhancer Binding Protein Alpha), CSF3R (Colony Stimulating Factor 3 Receptor)
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ABL1 (ABL proto-oncogene 1), ASXL1 (ASXL Transcriptional Regulator 1), BCOR (BCL6 Corepressor), BRAF (B-raf proto-oncogene), CEBPA (CCAAT Enhancer Binding Protein Alpha), CSF3R (Colony Stimulating Factor 3 Receptor), DNMT3A (DNA methyltransferase 1), EZH2 (Enhancer of zeste 2 polycomb repressive complex 2 subunit), FLT3 (Fms-related tyrosine kinase 3), GATA2 (GATA Binding Protein 2), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), JAK2 (Janus kinase 2), KIT (KIT proto-oncogene, receptor tyrosine kinase), KRAS (KRAS proto-oncogene GTPase), MPL (MPL Proto-Oncogene, Thrombopoietin Receptor), MYD88 (MYD88 Innate Immune Signal Transduction Adaptor), NPM1 (Nucleophosmin 1), NRAS (Neuroblastoma RAS viral oncogene homolog), PHF6 (PHD Finger Protein 6), PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11), RUNX1 (RUNX Family Transcription Factor 1), SETBP1 (SET Binding Protein 1), SF3B1 (Splicing Factor 3b Subunit 1), SH2B3 (SH2B Adaptor Protein 3), SRSF2 (Serine and arginine rich splicing factor 2), STAG2 (Stromal Antigen 2), TET2 (Tet Methylcytosine Dioxygenase 2), TP53 (Tumor protein P53), U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1), WT1 (WT1 Transcription Factor)
Method:
Next-Generation Sequencing (NGS)
