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TEST:
Oncomine™ Myeloid MRD Assays

Type:
Laboratory Developed Test
Related tests:

Details

Evidence
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The new Ion Torrent™ Oncomine™ Myeloid MRD Assays (RUO) on the Ion GeneStudio™ S5 System offer a complete NGS solution for myeloid MRD detection. A DNA and an RNA assay are available to cover a wide range of myeloid MRD targets, including key single-nucleotide variants (SNVs), insertions and deletions (indels), tandem duplications, and key gene fusions. Detect important biomarkers like NPM1, PML-RARA, IDH1/2, BCR-ABL1, and FLT3 (ITD and TKD). The carefully curated targets on the panel are relevant for all major types of myeloid neoplasms, including acute myeloid leukemias (AML), myelodysplastic syndromes (MDS), and myeloproliferative neoplasms (MPN) samples.
Cancer:
Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm
Gene:
ABL1 (ABL proto-oncogene 1), ASXL1 (ASXL Transcriptional Regulator 1), BCOR (BCL6 Corepressor), BRAF (B-raf proto-oncogene), CEBPA (CCAAT Enhancer Binding Protein Alpha), CSF3R (Colony Stimulating Factor 3 Receptor)
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Method:
Next-Generation Sequencing (NGS)