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our Premium Content: News alerts, weekly reports and conference plannersTEST:TruSight Myeloid Sequencing Panel
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Company:
IlluminaType:
Laboratory Developed Test
Related tests:
The TruSight Myeloid Sequencing Panel uses expert-defined content and proven next-generation sequencing (NGS) technology to identify somatic variants in myeloid malignancies. The TruSight Myeloid Sequencing Panel covers 15 full genes (exons only) and 39 additional genes where oncogenic hotspots are covered, providing a comprehensive assessment of the key genes known to be involved in myeloid malignancies in a single test.
Cancer:
Acute Myelogenous Leukemia, Chronic Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm
Gene:
ABL1 (ABL proto-oncogene 1), ASXL1 (ASXL Transcriptional Regulator 1), ATRX (ATRX Chromatin Remodeler), BCOR (BCL6 Corepressor), BRAF (B-raf proto-oncogene), CALR (Calreticulin)
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ABL1 (ABL proto-oncogene 1), ASXL1 (ASXL Transcriptional Regulator 1), ATRX (ATRX Chromatin Remodeler), BCOR (BCL6 Corepressor), BRAF (B-raf proto-oncogene), CALR (Calreticulin), CBL (Cbl proto-oncogene), CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), CEBPA (CCAAT Enhancer Binding Protein Alpha), CSF3R (Colony Stimulating Factor 3 Receptor), CUX1 (cut like homeobox 1), DNMT3A (DNA methyltransferase 1), ETV6 (ETS Variant Transcription Factor 6), EZH2 (Enhancer of zeste 2 polycomb repressive complex 2 subunit), FBXW7 (F-Box And WD Repeat Domain Containing 7), FLT3 (Fms-related tyrosine kinase 3), GATA1 (GATA Binding Protein 1), GATA2 (GATA Binding Protein 2), GNAS (GNAS Complex Locus), HRAS (Harvey rat sarcoma viral oncogene homolog), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), IKZF1 (IKAROS Family Zinc Finger 1), JAK2 (Janus kinase 2), JAK3 (Janus Kinase 3), KDM6A (Lysine Demethylase 6A), KIT (KIT proto-oncogene, receptor tyrosine kinase), KMT2A (Lysine Methyltransferase 2A), KRAS (KRAS proto-oncogene GTPase), MPL (MPL Proto-Oncogene, Thrombopoietin Receptor), MYD88 (MYD88 Innate Immune Signal Transduction Adaptor), NOTCH1 (Notch 1), NPM1 (Nucleophosmin 1), NRAS (Neuroblastoma RAS viral oncogene homolog), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PHF6 (PHD Finger Protein 6), PTEN (Phosphatase and tensin homolog), PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11), RAD21 (RAD21 Cohesin Complex Component), RUNX1 (RUNX Family Transcription Factor 1), SETBP1 (SET Binding Protein 1), SF3B1 (Splicing Factor 3b Subunit 1), SRSF2 (Serine and arginine rich splicing factor 2), STAG2 (Stromal Antigen 2), TET2 (Tet Methylcytosine Dioxygenase 2), TP53 (Tumor protein P53), U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1), WT1 (WT1 Transcription Factor), ZRSR2 (Zinc Finger CCCH-Type, RNA Binding Motif And Serine/Arginine Rich 2)
Method:
Next-Generation Sequencing (NGS)
