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DRUG:

M1231

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Company:

EMD Serono, Sutro Biopharma

Drug class:

Microtubule inhibitor, EGFR-targeted antibody-drug conjugate, MUC1-targeted antibody-drug conjugate

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estramustine (0)

Nectin-4 ADC (0)

vintafolide (0)

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mebendazole (0)

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MUC1 expression + EGFR expression	Esophageal Squamous Cell Carcinoma	MUC1 expression + EGFR expression	Esophageal Squamous Cell Carcinoma	M1231 Sensitive: C2 – Inclusion Criteria M1231 Sensitive : C2	M1231 Sensitive: C2 – Inclusion Criteria M1231 Sensitive : C2
MUC1 expression + EGFR expression	Non Small Cell Lung Cancer	MUC1 expression + EGFR expression	Non Small Cell Lung Cancer	M1231 Sensitive: C2 – Inclusion Criteria M1231 Sensitive : C2	M1231 Sensitive: C2 – Inclusion Criteria M1231 Sensitive : C2
EGFR mutation	Non Small Cell Lung Cancer	EGFR mutation	Non Small Cell Lung Cancer	M1231 Sensitive: D – Preclinical M1231 Sensitive : D	M1231 Sensitive: D – Preclinical M1231 Sensitive : D