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DRUG:

HTI-1511

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Company:

Halozyme

Drug class:

Microtubule inhibitor, EGFR-targeted antibody-drug conjugate

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EGFR overexpression + KRAS 13D	Triple Negative Breast Cancer	EGFR overexpression + KRAS 13D	Triple Negative Breast Cancer	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D
EGFR overexpression + BRAF V600E	Colorectal Cancer	EGFR overexpression + BRAF V600E	Colorectal Cancer	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D
EGFR overexpression + BRAF mutation	Colorectal Cancer	EGFR overexpression + BRAF mutation	Colorectal Cancer	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D
EGFR overexpression + KRAS mutation	Non Small Cell Lung Cancer	EGFR overexpression + KRAS mutation	Non Small Cell Lung Cancer	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D
EGFR overexpression	Pancreatic Cancer	EGFR overexpression	Pancreatic Cancer	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D
EGFR overexpression	Non Small Cell Lung Cancer	EGFR overexpression	Non Small Cell Lung Cancer	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D
EGFR overexpression	Squamous Cell Carcinoma of Head and Neck	EGFR overexpression	Squamous Cell Carcinoma of Head and Neck	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D	HTI-1511 Sensitive: D – Preclinical HTI-1511 Sensitive : D