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DRUG:

SGN-CD228A

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Company:

Pfizer

Drug class:

Microtubule inhibitor, CD228-targeted antibody-drug conjugate

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MFI2 expression	Triple Negative Breast Cancer	MFI2 expression	Triple Negative Breast Cancer	SGN-CD228A Sensitive: D – Preclinical SGN-CD228A Sensitive : D	SGN-CD228A Sensitive: D – Preclinical SGN-CD228A Sensitive : D
MELTF expression	Solid Tumor	MELTF expression	Solid Tumor	SGN-CD228A Sensitive: D – Preclinical SGN-CD228A Sensitive : D	SGN-CD228A Sensitive: D – Preclinical SGN-CD228A Sensitive : D
MELTF overexpression	Triple Negative Breast Cancer	MELTF overexpression	Triple Negative Breast Cancer	SGN-CD228A Sensitive: D – Preclinical SGN-CD228A Sensitive : D	SGN-CD228A Sensitive: D – Preclinical SGN-CD228A Sensitive : D
MELTF overexpression	Lung Non-Small Cell Squamous Cancer	MELTF overexpression	Lung Non-Small Cell Squamous Cancer	SGN-CD228A Sensitive: D – Preclinical SGN-CD228A Sensitive : D	SGN-CD228A Sensitive: D – Preclinical SGN-CD228A Sensitive : D
MELTF overexpression	Melanoma	MELTF overexpression	Melanoma	SGN-CD228A Sensitive: D – Preclinical SGN-CD228A Sensitive : D	SGN-CD228A Sensitive: D – Preclinical SGN-CD228A Sensitive : D