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DRUG:

SAR566658

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Company:

AbbVie, Sanofi

Drug class:

Microtubule inhibitor, CA6-targeted antibody-drug conjugate

Related drugs:

ado-trastuzumab emtansine (97)

eribulin mesylate (47)

brentuximab vedotin (29)

disitamab vedotin (27)

mirvetuximab soravtansine-gynx (16)

enfortumab vedotin-ejfv (14)

cabazitaxel (12)

ixabepilone (6)

LR004-VC-MMAE (5)

PF-06804103 (4)

PF-08046048 (4)

PF-08046047 (4)

belantamab mafodotin-blmf (3)

polatuzumab vedotin-piiq (3)

RGX-019-MMAE (3)

BAY 94-9343 (3)

IMAB027-vcMMAE (2)

PF-06650808 (2)

MF-TTZ-MMAE (1)

PF-06263507 (1)

PF-08046054 (1)

tisotumab vedotin-tftv (1)

estramustine (0)

vintafolide (0)

HuMax-AXL-ADC (0)

mebendazole (0)

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CA6 expression	Solid Tumor	CA6 expression	Solid Tumor	SAR566658 Sensitive: C3 – Early Trials SAR566658 Sensitive : C3	SAR566658 Sensitive: C3 – Early Trials SAR566658 Sensitive : C3
CA6 expression	Ovarian Cancer	CA6 expression	Ovarian Cancer	SAR566658 Sensitive: D – Preclinical SAR566658 Sensitive : D	SAR566658 Sensitive: D – Preclinical SAR566658 Sensitive : D
CA6 expression	Bladder Cancer	CA6 expression	Bladder Cancer	SAR566658 Sensitive: D – Preclinical SAR566658 Sensitive : D	SAR566658 Sensitive: D – Preclinical SAR566658 Sensitive : D
CA6 expression	Cervical Cancer	CA6 expression	Cervical Cancer	SAR566658 Sensitive: D – Preclinical SAR566658 Sensitive : D	SAR566658 Sensitive: D – Preclinical SAR566658 Sensitive : D
CA6 expression	Pancreatic Cancer	CA6 expression	Pancreatic Cancer	SAR566658 Sensitive: D – Preclinical SAR566658 Sensitive : D	SAR566658 Sensitive: D – Preclinical SAR566658 Sensitive : D