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DRUG:

sonesitatug vedotin (AZD0901)

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Company:

AstraZeneca, Keymed Biosciences, Lepu Med

Drug class:

Microtubule inhibitor, CLDN18.2-targeted antibody-drug conjugate

Related drugs:

ado-trastuzumab emtansine (97)

eribulin mesylate (47)

brentuximab vedotin (29)

disitamab vedotin (27)

mirvetuximab soravtansine-gynx (16)

enfortumab vedotin-ejfv (14)

cabazitaxel (12)

ixabepilone (6)

LR004-VC-MMAE (5)

PF-06804103 (4)

PF-08046048 (4)

PF-08046047 (4)

belantamab mafodotin-blmf (3)

polatuzumab vedotin-piiq (3)

RGX-019-MMAE (3)

BAY 94-9343 (3)

IMAB027-vcMMAE (2)

PF-06650808 (2)

MF-TTZ-MMAE (1)

PF-06263507 (1)

PF-08046054 (1)

tisotumab vedotin-tftv (1)

estramustine (0)

vintafolide (0)

HuMax-AXL-ADC (0)

mebendazole (0)

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No biomarker	Gastroesophageal Junction Adenocarcinoma	No biomarker	Gastroesophageal Junction Adenocarcinoma	AZD0901 Sensitive: B - Late Trials AZD0901 Sensitive : B	AZD0901 Sensitive: B - Late Trials AZD0901 Sensitive : B
No biomarker	Gastric Cancer	No biomarker	Gastric Cancer	AZD0901 Sensitive: B - Late Trials AZD0901 Sensitive : B	AZD0901 Sensitive: B - Late Trials AZD0901 Sensitive : B
CLDN18.2 positive	Gastroesophageal Junction Adenocarcinoma	CLDN18.2 positive	Gastroesophageal Junction Adenocarcinoma	AZD0901 Sensitive: C2 – Inclusion Criteria AZD0901 Sensitive : C2	AZD0901 Sensitive: C2 – Inclusion Criteria AZD0901 Sensitive : C2
CLDN18.2 positive	Gastric Cancer	CLDN18.2 positive	Gastric Cancer	AZD0901 Sensitive: C2 – Inclusion Criteria AZD0901 Sensitive : C2	AZD0901 Sensitive: C2 – Inclusion Criteria AZD0901 Sensitive : C2