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DRUG:

tusamitamab ravtansine (SAR408701)

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News alerts, weekly reports and conference planners

Company:

AbbVie, Innovent Biologics, Sanofi

Drug class:

Microtubule inhibitor, CEACAM5-targeted antibody-drug conjugate

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CEACAM5 positive	Gastric Cancer	CEACAM5 positive	Gastric Cancer	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2
CEACAM5 positive	Lung Cancer	CEACAM5 positive	Lung Cancer	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2
CEACAM5 positive	Colorectal Cancer	CEACAM5 positive	Colorectal Cancer	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2
CEACAM5 expression	Lung Non-Squamous Non-Small Cell Cancer	CEACAM5 expression	Lung Non-Squamous Non-Small Cell Cancer	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2
CEACAM5 expression	Gastric Cancer	CEACAM5 expression	Gastric Cancer	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2
CEACAM5 expression	Solid Tumor	CEACAM5 expression	Solid Tumor	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2	SAR408701 Sensitive: C2 – Inclusion Criteria SAR408701 Sensitive : C2
CEACAM5 overexpression	Lung Non-Squamous Non-Small Cell Cancer	CEACAM5 overexpression	Lung Non-Squamous Non-Small Cell Cancer	SAR408701 Sensitive: C3 – Early Trials SAR408701 Sensitive : C3	SAR408701 Sensitive: C3 – Early Trials SAR408701 Sensitive : C3
CEACAM5 overexpression	Gastric Cancer	CEACAM5 overexpression	Gastric Cancer	SAR408701 Sensitive: C3 – Early Trials SAR408701 Sensitive : C3	SAR408701 Sensitive: C3 – Early Trials SAR408701 Sensitive : C3
CEACAM5 overexpression	Lung Non-Squamous Non-Small Cell Cancer	CEACAM5 overexpression	Lung Non-Squamous Non-Small Cell Cancer	pembrolizumab + SAR408701 Sensitive: C3 – Early Trials pembrolizumab + SAR408701 Sensitive : C3	pembrolizumab + SAR408701 Sensitive: C3 – Early Trials pembrolizumab + SAR408701 Sensitive : C3
CEACAM5 overexpression	Lung Non-Squamous Non-Small Cell Cancer	CEACAM5 overexpression	Lung Non-Squamous Non-Small Cell Cancer	ramucirumab + SAR408701 Sensitive: C3 – Early Trials ramucirumab + SAR408701 Sensitive : C3	ramucirumab + SAR408701 Sensitive: C3 – Early Trials ramucirumab + SAR408701 Sensitive : C3
CEACAM5 expression	Pancreatic Cancer	CEACAM5 expression	Pancreatic Cancer	SAR408701 Sensitive: D – Preclinical SAR408701 Sensitive : D	SAR408701 Sensitive: D – Preclinical SAR408701 Sensitive : D
KRAS mutation	Lung Non-Squamous Non-Small Cell Cancer	KRAS mutation	Lung Non-Squamous Non-Small Cell Cancer	SAR408701 Sensitive: D – Preclinical SAR408701 Sensitive : D	SAR408701 Sensitive: D – Preclinical SAR408701 Sensitive : D