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DRUG:

LY3076226

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Company:

AbbVie, Eli Lilly

Drug class:

Microtubule inhibitor, FGFR3-targeted antibody-drug conjugate

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FGFR3-TACC3 fusion	Lung Cancer	FGFR3-TACC3 fusion	Lung Cancer	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D
FGFR3-TACC3 fusion	Bladder Cancer	FGFR3-TACC3 fusion	Bladder Cancer	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D
FGFR3-BAIAP2L1 fusion	Bladder Cancer	FGFR3-BAIAP2L1 fusion	Bladder Cancer	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D
FGFR3 R248C	Bladder Cancer	FGFR3 R248C	Bladder Cancer	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D
FGFR3 S249C	Bladder Cancer	FGFR3 S249C	Bladder Cancer	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D
FGFR3 G370C	Bladder Cancer	FGFR3 G370C	Bladder Cancer	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D	LY3076226 Sensitive: D – Preclinical LY3076226 Sensitive : D