Login
Evidence Feed
About
Diagnostics
New
Top genes
FAQ
Contact us
^
Login
Contact us
to learn more about
our Premium Content: News alerts, weekly reports and conference planners
DRUG:
Kadcyla (ado-trastuzumab emtansine)
i
Other names:
PRO132365, R3502, RG 3502, RG3502, T-DM1, trastuzumab-DM1, trastuzumab-MCC-DM1, trastuzumab-mertansine, Herceptin-DM1, RO5304020, PRO 132365, RO 5304020, PRO-132365, RO-5304020
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Associations
(97)
News
Trials
Company:
AbbVie, Roche
Drug class:
Microtubule inhibitor, HER2-targeted antibody-drug conjugate
Related drugs:
‹
eribulin mesylate (47)
brentuximab vedotin (29)
disitamab vedotin (27)
mirvetuximab soravtansine-gynx (16)
enfortumab vedotin-ejfv (14)
cabazitaxel (12)
SAR408701 (12)
ABBV-399 (11)
JNJ-0683 (9)
SGN-ALPV (8)
STRO-002 (8)
HTI-1511 (7)
IMGC936 (7)
ixabepilone (6)
LY3076226 (6)
MRG003 (6)
EO-3021 (5)
LR004-VC-MMAE (5)
SAR566658 (5)
SGN-CD228A (5)
ASN004 (4)
LCB84 (4)
PF-06804103 (4)
SAR428926 (4)
MORAb-202 (4)
PF-08046048 (4)
BAY1129980 (4)
PF-08046047 (4)
AZD0901 (4)
MK-2140 (4)
3D1-MMAE (3)
ASG 5ME (3)
belantamab mafodotin-blmf (3)
CBP-1008 (3)
LOP628 (3)
M1231 (3)
polatuzumab vedotin-piiq (3)
RGX-019-MMAE (3)
SHR-A1403 (3)
TEQ102 (3)
XMT-1522 (3)
BAY 94-9343 (3)
ABT-414 (3)
BA3011 (3)
LM-302 (3)
IKS014 (3)
MRG002 (3)
XMT-1536 (3)
ZW49 (3)
AMG 595 (2)
BB-1701 (2)
BB-1705 (2)
IMAB027-vcMMAE (2)
JBH492 (2)
MORAb-109 (2)
MYTX-011 (2)
NN3201 (2)
OBT076 (2)
PF-06650808 (2)
RG7600 (2)
TORL-1-23 (2)
XMT-1592 (2)
STRO-001 (2)
ABBV-647 (2)
E7389-LF (2)
CDX-011 (2)
DNIB0600A (2)
IMGN901 (2)
ABBV-221 (2)
PM184 (2)
DP303c (2)
BT8009 (2)
9MW2821 (1)
AGS62P1 (1)
AGS67E (1)
ALT-P7 (1)
ARC-02 (1)
ATG-022 (1)
AZD0305 (1)
AbGn-107 (1)
McSAF 03 (1)
BAT8001 (1)
BAT8003 (1)
BAY79-4620 (1)
BCY6033 (1)
BIIB015 (1)
BRY812 (1)
BVX001 (1)
CDX-014 (1)
DLYE5953A (1)
F0002-ADC (1)
GQ1001 (1)
MEDI4276 (1)
MF-TTZ-MMAE (1)
MRG001 (1)
McSAF 02 (1)
OBI-998 (1)
OBI-999 (1)
Oba01 (1)
PF-06263507 (1)
PF-08046054 (1)
PSMA ADC (1)
RG7882 (1)
SGN-CD48A (1)
STI-6129 (1)
TAA013 (1)
TRPH-222 (1)
tisotumab vedotin-tftv (1)
(1)
INT230-6 (1)
SGN-LIV1A (1)
W0101 (1)
IMGN-151 (1)
CX-2009 (1)
ASG-15ME (1)
RG7450 (1)
AMG 172 (0)
AVE9633 (0)
AVID100 (0)
BT1718 (0)
CD6-ADC (0)
CX-2029 (0)
DX126-262 (0)
E7130 (0)
EBC-129 (0)
estramustine (0)
FG-3246 (0)
GMF-1A3 (0)
HKT288 (0)
INA03 (0)
JS108 (0)
vinflunine (0)
MBRC-101 (0)
MEDI-547 (0)
MRG004A (0)
Nectin-4 ADC (0)
OMTX705 (0)
PCA062 (0)
RC108 (0)
SGN-STNV (0)
SHR-4602 (0)
(0)
TPI 287 (0)
TRS005 (0)
vintafolide (0)
BAY1187982 (0)
MPB-1734 (0)
RC118 (0)
SAR3419 (0)
SGN-CD19A (0)
HuMax-AXL-ADC (0)
EC1456 (0)
DCDS0780A (0)
BT-062 (0)
BMS-986352 (0)
IMGN289 (0)
mebendazole (0)
PYX-201 (0)
RC88 (0)
DEBIO 1562 (0)
RG7593 (0)
XB002 (0)
ABBV-085 (0)
UTD1 (0)
fam-trastuzumab deruxtecan-nxki (90)
SHR-A1811 (15)
trastuzumab duocarmazine (6)
A166 (6)
MM-302 (4)
SBT6050 (4)
BNT323 (4)
BL-M07D1 (3)
ORM-5029 (2)
PRO1102 (2)
XMT-2056 (2)
ADC2122 (1)
DAN-311 (1)
DHES0815A (1)
MYX2449 (1)
YH012 (1)
BT2111 (1)
ADCT-502 (0)
BAT8010 (0)
GQ1007 (0)
IBI-354 (0)
JSKN003 (0)
TQB2102 (0)
BI-CON-02 (0)
eribulin mesylate (47)
brentuximab vedotin (29)
disitamab vedotin (27)
mirvetuximab soravtansine-gynx (16)
enfortumab vedotin-ejfv (14)
cabazitaxel (12)
SAR408701 (12)
ABBV-399 (11)
JNJ-0683 (9)
SGN-ALPV (8)
STRO-002 (8)
HTI-1511 (7)
IMGC936 (7)
ixabepilone (6)
LY3076226 (6)
MRG003 (6)
EO-3021 (5)
LR004-VC-MMAE (5)
SAR566658 (5)
SGN-CD228A (5)
ASN004 (4)
LCB84 (4)
PF-06804103 (4)
SAR428926 (4)
MORAb-202 (4)
PF-08046048 (4)
BAY1129980 (4)
PF-08046047 (4)
AZD0901 (4)
MK-2140 (4)
3D1-MMAE (3)
ASG 5ME (3)
belantamab mafodotin-blmf (3)
CBP-1008 (3)
LOP628 (3)
M1231 (3)
polatuzumab vedotin-piiq (3)
RGX-019-MMAE (3)
SHR-A1403 (3)
TEQ102 (3)
XMT-1522 (3)
BAY 94-9343 (3)
ABT-414 (3)
BA3011 (3)
LM-302 (3)
IKS014 (3)
MRG002 (3)
XMT-1536 (3)
ZW49 (3)
AMG 595 (2)
BB-1701 (2)
BB-1705 (2)
IMAB027-vcMMAE (2)
JBH492 (2)
MORAb-109 (2)
MYTX-011 (2)
NN3201 (2)
OBT076 (2)
PF-06650808 (2)
RG7600 (2)
TORL-1-23 (2)
XMT-1592 (2)
STRO-001 (2)
ABBV-647 (2)
E7389-LF (2)
CDX-011 (2)
DNIB0600A (2)
IMGN901 (2)
ABBV-221 (2)
PM184 (2)
DP303c (2)
BT8009 (2)
9MW2821 (1)
AGS62P1 (1)
AGS67E (1)
ALT-P7 (1)
ARC-02 (1)
ATG-022 (1)
AZD0305 (1)
AbGn-107 (1)
McSAF 03 (1)
BAT8001 (1)
BAT8003 (1)
BAY79-4620 (1)
BCY6033 (1)
BIIB015 (1)
BRY812 (1)
BVX001 (1)
CDX-014 (1)
DLYE5953A (1)
F0002-ADC (1)
GQ1001 (1)
MEDI4276 (1)
MF-TTZ-MMAE (1)
MRG001 (1)
McSAF 02 (1)
OBI-998 (1)
OBI-999 (1)
Oba01 (1)
PF-06263507 (1)
PF-08046054 (1)
PSMA ADC (1)
RG7882 (1)
SGN-CD48A (1)
STI-6129 (1)
TAA013 (1)
TRPH-222 (1)
tisotumab vedotin-tftv (1)
(1)
INT230-6 (1)
SGN-LIV1A (1)
W0101 (1)
IMGN-151 (1)
CX-2009 (1)
ASG-15ME (1)
RG7450 (1)
AMG 172 (0)
AVE9633 (0)
AVID100 (0)
BT1718 (0)
CD6-ADC (0)
CX-2029 (0)
DX126-262 (0)
E7130 (0)
EBC-129 (0)
estramustine (0)
FG-3246 (0)
GMF-1A3 (0)
HKT288 (0)
INA03 (0)
JS108 (0)
vinflunine (0)
MBRC-101 (0)
MEDI-547 (0)
MRG004A (0)
Nectin-4 ADC (0)
OMTX705 (0)
PCA062 (0)
RC108 (0)
SGN-STNV (0)
SHR-4602 (0)
(0)
TPI 287 (0)
TRS005 (0)
vintafolide (0)
BAY1187982 (0)
MPB-1734 (0)
RC118 (0)
SAR3419 (0)
SGN-CD19A (0)
HuMax-AXL-ADC (0)
EC1456 (0)
DCDS0780A (0)
BT-062 (0)
BMS-986352 (0)
IMGN289 (0)
mebendazole (0)
PYX-201 (0)
RC88 (0)
DEBIO 1562 (0)
RG7593 (0)
XB002 (0)
ABBV-085 (0)
UTD1 (0)
fam-trastuzumab deruxtecan-nxki (90)
SHR-A1811 (15)
trastuzumab duocarmazine (6)
A166 (6)
MM-302 (4)
SBT6050 (4)
BNT323 (4)
BL-M07D1 (3)
ORM-5029 (2)
PRO1102 (2)
XMT-2056 (2)
ADC2122 (1)
DAN-311 (1)
DHES0815A (1)
MYX2449 (1)
YH012 (1)
BT2111 (1)
ADCT-502 (0)
BAT8010 (0)
GQ1007 (0)
IBI-354 (0)
JSKN003 (0)
TQB2102 (0)
BI-CON-02 (0)
›
Associations
(97)
News
Trials
VERI cancer hierarchy
Reset Filters
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
ado-trastuzumab emtansine
Sensitive: A1 - Approval
ado-trastuzumab emtansine
Sensitive
:
A1
ado-trastuzumab emtansine
Sensitive: A1 - Approval
ado-trastuzumab emtansine
Sensitive
:
A1
HER-2 mutation
Non Small Cell Lung Cancer
HER-2 mutation
Non Small Cell Lung Cancer
ado-trastuzumab emtansine
Sensitive: A2 - Guideline
ado-trastuzumab emtansine
Sensitive
:
A2
ado-trastuzumab emtansine
Sensitive: A2 - Guideline
ado-trastuzumab emtansine
Sensitive
:
A2
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
pertuzumab + ado-trastuzumab emtansine
Sensitive: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Sensitive
:
B
pertuzumab + ado-trastuzumab emtansine
Sensitive: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Sensitive
:
B
ERBB3 expression
HER2 Positive Breast Cancer
ERBB3 expression
HER2 Positive Breast Cancer
ado-trastuzumab emtansine
Sensitive: B - Late Trials
ado-trastuzumab emtansine
Sensitive
:
B
ado-trastuzumab emtansine
Sensitive: B - Late Trials
ado-trastuzumab emtansine
Sensitive
:
B
PTEN expression
HER2 Positive Breast Cancer
PTEN expression
HER2 Positive Breast Cancer
ado-trastuzumab emtansine
Resistant: B - Late Trials
ado-trastuzumab emtansine
Resistant
:
B
ado-trastuzumab emtansine
Resistant: B - Late Trials
ado-trastuzumab emtansine
Resistant
:
B
EGFR expression
HER2 Positive Breast Cancer
EGFR expression
HER2 Positive Breast Cancer
ado-trastuzumab emtansine
Sensitive: B - Late Trials
ado-trastuzumab emtansine
Sensitive
:
B
ado-trastuzumab emtansine
Sensitive: B - Late Trials
ado-trastuzumab emtansine
Sensitive
:
B
PIK3CA K111N
Breast Cancer
PIK3CA K111N
Breast Cancer
ado-trastuzumab emtansine
Sensitive: B - Late Trials
ado-trastuzumab emtansine
Sensitive
:
B
ado-trastuzumab emtansine
Sensitive: B - Late Trials
ado-trastuzumab emtansine
Sensitive
:
B
RAB5A expression
Breast Cancer
RAB5A expression
Breast Cancer
ado-trastuzumab emtansine
Sensitive: B - Late Trials
ado-trastuzumab emtansine
Sensitive
:
B
ado-trastuzumab emtansine
Sensitive: B - Late Trials
ado-trastuzumab emtansine
Sensitive
:
B
PIK3CA mutation
HER2 Positive Breast Cancer
PIK3CA mutation
HER2 Positive Breast Cancer
pertuzumab + ado-trastuzumab emtansine
Resistant: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Resistant
:
B
pertuzumab + ado-trastuzumab emtansine
Resistant: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Resistant
:
B
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
pertuzumab + ado-trastuzumab emtansine
Sensitive: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Sensitive
:
B
pertuzumab + ado-trastuzumab emtansine
Sensitive: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Sensitive
:
B
HER-2 amplification
HER2 Positive Breast Cancer
HER-2 amplification
HER2 Positive Breast Cancer
pertuzumab + ado-trastuzumab emtansine
Sensitive: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Sensitive
:
B
pertuzumab + ado-trastuzumab emtansine
Sensitive: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Sensitive
:
B
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
ado-trastuzumab emtansine + tucatinib
Sensitive: B - Late Trials
ado-trastuzumab emtansine + tucatinib
Sensitive
:
B
ado-trastuzumab emtansine + tucatinib
Sensitive: B - Late Trials
ado-trastuzumab emtansine + tucatinib
Sensitive
:
B
HER-2 positive
Colon Cancer
HER-2 positive
Colon Cancer
ado-trastuzumab emtansine
Sensitive: C1 - Off-label
ado-trastuzumab emtansine
Sensitive
:
C1
ado-trastuzumab emtansine
Sensitive: C1 - Off-label
ado-trastuzumab emtansine
Sensitive
:
C1
HER-2 positive
Gastric Cancer
HER-2 positive
Gastric Cancer
ado-trastuzumab emtansine
Sensitive: C1 - Off-label
ado-trastuzumab emtansine
Sensitive
:
C1
ado-trastuzumab emtansine
Sensitive: C1 - Off-label
ado-trastuzumab emtansine
Sensitive
:
C1
HER-2 positive
Pancreatic Cancer
HER-2 positive
Pancreatic Cancer
ado-trastuzumab emtansine
Sensitive: C1 - Off-label
ado-trastuzumab emtansine
Sensitive
:
C1
ado-trastuzumab emtansine
Sensitive: C1 - Off-label
ado-trastuzumab emtansine
Sensitive
:
C1
HER-2 positive
Bladder Cancer
HER-2 positive
Bladder Cancer
ado-trastuzumab emtansine
Sensitive: C1 - Off-label
ado-trastuzumab emtansine
Sensitive
:
C1
ado-trastuzumab emtansine
Sensitive: C1 - Off-label
ado-trastuzumab emtansine
Sensitive
:
C1
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 overexpression
HER2 Positive Breast Cancer
HER-2 overexpression
HER2 Positive Breast Cancer
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 amplification
HER2 Positive Breast Cancer
HER-2 amplification
HER2 Positive Breast Cancer
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 amplification
Salivary Gland Cancer
HER-2 amplification
Salivary Gland Cancer
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 amplification
Endometrial Cancer
HER-2 amplification
Endometrial Cancer
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 amplification
Lung Cancer
HER-2 amplification
Lung Cancer
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 amplification
Gastroesophageal Junction Adenocarcinoma
HER-2 amplification
Gastroesophageal Junction Adenocarcinoma
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
palbociclib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
palbociclib + ado-trastuzumab emtansine
Sensitive
:
C2
palbociclib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
palbociclib + ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 overexpression
HER2 Positive Breast Cancer
HER-2 overexpression
HER2 Positive Breast Cancer
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 overexpression
Breast Cancer
HER-2 overexpression
Breast Cancer
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 underexpression
Breast Cancer
HER-2 underexpression
Breast Cancer
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
ado-trastuzumab emtansine
Sensitive: C3 – Early Trials
ado-trastuzumab emtansine
Sensitive
:
C3
ado-trastuzumab emtansine
Sensitive: C3 – Early Trials
ado-trastuzumab emtansine
Sensitive
:
C3
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
atezolizumab + ado-trastuzumab emtansine
Resistant: C3 – Early Trials
atezolizumab + ado-trastuzumab emtansine
Resistant
:
C3
atezolizumab + ado-trastuzumab emtansine
Resistant: C3 – Early Trials
atezolizumab + ado-trastuzumab emtansine
Resistant
:
C3
HER-2 underexpression
Lung Adenocarcinoma
HER-2 underexpression
Lung Adenocarcinoma
ado-trastuzumab emtansine
Sensitive: C3 – Early Trials
ado-trastuzumab emtansine
Sensitive
:
C3
ado-trastuzumab emtansine
Sensitive: C3 – Early Trials
ado-trastuzumab emtansine
Sensitive
:
C3
HER-2 exon 20 insertion
Lung Adenocarcinoma
HER-2 exon 20 insertion
Lung Adenocarcinoma
ado-trastuzumab emtansine
Sensitive: C3 – Early Trials
ado-trastuzumab emtansine
Sensitive
:
C3
ado-trastuzumab emtansine
Sensitive: C3 – Early Trials
ado-trastuzumab emtansine
Sensitive
:
C3
HER-2 mutation
Lung Adenocarcinoma
HER-2 mutation
Lung Adenocarcinoma
ado-trastuzumab emtansine
Sensitive: C3 – Early Trials
ado-trastuzumab emtansine
Sensitive
:
C3
ado-trastuzumab emtansine
Sensitive: C3 – Early Trials
ado-trastuzumab emtansine
Sensitive
:
C3
^
^
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login