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DRUG:

izeltabart tapatansine (IMGC936)

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News alerts, weekly reports and conference planners

Company:

AbbVie, MacroGenics

Drug class:

Microtubule inhibitor, ADAM9-targeted antibody-drug conjugate

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estramustine (0)

Nectin-4 ADC (0)

vintafolide (0)

HuMax-AXL-ADC (0)

mebendazole (0)

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ADAM9 expression	Solid Tumor	ADAM9 expression	Solid Tumor	IMGC936 Sensitive: C2 – Inclusion Criteria IMGC936 Sensitive : C2	IMGC936 Sensitive: C2 – Inclusion Criteria IMGC936 Sensitive : C2
ADAM9 expression	Gastric Cancer	ADAM9 expression	Gastric Cancer	IMGC936 Sensitive: C2 – Inclusion Criteria IMGC936 Sensitive : C2	IMGC936 Sensitive: C2 – Inclusion Criteria IMGC936 Sensitive : C2
ADAM9 expression	Non Small Cell Lung Cancer	ADAM9 expression	Non Small Cell Lung Cancer	IMGC936 Sensitive: C2 – Inclusion Criteria IMGC936 Sensitive : C2	IMGC936 Sensitive: C2 – Inclusion Criteria IMGC936 Sensitive : C2
ADAM9 overexpression	Triple Negative Breast Cancer	ADAM9 overexpression	Triple Negative Breast Cancer	IMGC936 Sensitive: D – Preclinical IMGC936 Sensitive : D	IMGC936 Sensitive: D – Preclinical IMGC936 Sensitive : D
ADAM9 overexpression	Non Small Cell Lung Cancer	ADAM9 overexpression	Non Small Cell Lung Cancer	IMGC936 Sensitive: D – Preclinical IMGC936 Sensitive : D	IMGC936 Sensitive: D – Preclinical IMGC936 Sensitive : D
ADAM9 positive	Solid Tumor	ADAM9 positive	Solid Tumor	IMGC936 Sensitive: D – Preclinical IMGC936 Sensitive : D	IMGC936 Sensitive: D – Preclinical IMGC936 Sensitive : D
ADAM9 expression	Colorectal Cancer	ADAM9 expression	Colorectal Cancer	IMGC936 Sensitive: D – Preclinical IMGC936 Sensitive : D	IMGC936 Sensitive: D – Preclinical IMGC936 Sensitive : D