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DRUG:
Halaven (eribulin mesylate)
i
Other names:
E7389, ER-086526, B1939 mesylate, B-1939, Halichondrin B analog, NSC-707389
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Associations
(47)
News
Trials
Company:
Eisai, Knight Therap, Shenzhen Kexing Pharma
Drug class:
Microtubule inhibitor, CBP inhibitor, β-catenin inhibitor
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PF-06804103 (4)
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PF-08046047 (4)
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AMG 595 (2)
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CDX-011 (2)
DNIB0600A (2)
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BT8009 (2)
9MW2821 (1)
AGS62P1 (1)
AGS67E (1)
ALT-P7 (1)
ARC-02 (1)
ATG-022 (1)
AZD0305 (1)
AbGn-107 (1)
McSAF 03 (1)
BAT8001 (1)
BAT8003 (1)
BAY79-4620 (1)
BCY6033 (1)
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DLYE5953A (1)
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MF-TTZ-MMAE (1)
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McSAF 02 (1)
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OBI-999 (1)
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PSMA ADC (1)
RG7882 (1)
SGN-CD48A (1)
STI-6129 (1)
TAA013 (1)
TRPH-222 (1)
tisotumab vedotin-tftv (1)
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INT230-6 (1)
SGN-LIV1A (1)
W0101 (1)
IMGN-151 (1)
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ASG-15ME (1)
RG7450 (1)
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mebendazole (0)
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RG7593 (0)
XB002 (0)
ABBV-085 (0)
UTD1 (0)
PRI724 (5)
CCS1477 (4)
FT-6876 (1)
AU-18069 (0)
AUR-107 (0)
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ado-trastuzumab emtansine (97)
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HTI-1511 (7)
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MRG003 (6)
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SAR566658 (5)
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AZD0901 (4)
LCB84 (4)
PF-06804103 (4)
SAR428926 (4)
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PF-08046048 (4)
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PF-08046047 (4)
MK-2140 (4)
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ASG 5ME (3)
BMS-986476 (3)
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CBP-1008 (3)
LOP628 (3)
M1231 (3)
polatuzumab vedotin-piiq (3)
RGX-019-MMAE (3)
SHR-A1403 (3)
TEQ102 (3)
XMT-1522 (3)
BAY 94-9343 (3)
ABT-414 (3)
BA3011 (3)
IKS014 (3)
MRG002 (3)
XMT-1536 (3)
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PF-06650808 (2)
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STRO-001 (2)
TORL-1-23 (2)
XMT-1592 (2)
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E7389-LF (2)
CDX-011 (2)
DNIB0600A (2)
IMGN901 (2)
ABBV-221 (2)
PM184 (2)
DP303c (2)
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AbGn-107 (1)
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BAT8003 (1)
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CDX-014 (1)
DLYE5953A (1)
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GQ1001 (1)
MEDI4276 (1)
MF-TTZ-MMAE (1)
MRG001 (1)
McSAF 02 (1)
OBI-998 (1)
OBI-999 (1)
Oba01 (1)
PF-06263507 (1)
PF-08046054 (1)
PSMA ADC (1)
RG7882 (1)
SGN-CD48A (1)
STI-6129 (1)
TAA013 (1)
TRPH-222 (1)
tisotumab vedotin-tftv (1)
(1)
INT230-6 (1)
SGN-LIV1A (1)
W0101 (1)
IMGN-151 (1)
CX-2009 (1)
ASG-15ME (1)
RG7450 (1)
AMG 172 (0)
AVE9633 (0)
AVID100 (0)
BT1718 (0)
CD6-ADC (0)
CX-2029 (0)
DX126-262 (0)
E7130 (0)
EBC-129 (0)
estramustine (0)
FG-3246 (0)
GMF-1A3 (0)
HKT288 (0)
INA03 (0)
JS108 (0)
vinflunine (0)
MBRC-101 (0)
MEDI-547 (0)
MRG004A (0)
Nectin-4 ADC (0)
OMTX705 (0)
PCA062 (0)
RC108 (0)
RC118 (0)
SGN-STNV (0)
SHR-4602 (0)
(0)
TPI 287 (0)
TRS005 (0)
vintafolide (0)
BAY1187982 (0)
MPB-1734 (0)
SAR3419 (0)
SGN-CD19A (0)
HuMax-AXL-ADC (0)
EC1456 (0)
DCDS0780A (0)
BT-062 (0)
BMS-986352 (0)
IMGN289 (0)
mebendazole (0)
PYX-201 (0)
RC88 (0)
DEBIO 1562 (0)
RG7593 (0)
XB002 (0)
ABBV-085 (0)
UTD1 (0)
PRI724 (5)
CCS1477 (4)
FT-6876 (1)
AU-18069 (0)
AUR-107 (0)
E7386 (0)
EP31670 (0)
NEO1132 (0)
BC2059 (2)
FOG-001 (0)
KY1022 (0)
MCI-030 (0)
MRX34 (0)
›
Associations
(47)
News
Trials
VERI cancer hierarchy
Reset Filters
No biomarker
Liposarcoma
No biomarker
Liposarcoma
eribulin mesylate
Sensitive: A1 - Approval
eribulin mesylate
Sensitive
:
A1
eribulin mesylate
Sensitive: A1 - Approval
eribulin mesylate
Sensitive
:
A1
No biomarker
Breast Cancer
No biomarker
Breast Cancer
eribulin mesylate
Sensitive: A1 - Approval
eribulin mesylate
Sensitive
:
A1
eribulin mesylate
Sensitive: A1 - Approval
eribulin mesylate
Sensitive
:
A1
HER-2 negative
HER2 Negative Breast Cancer
HER-2 negative
HER2 Negative Breast Cancer
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
BRCA2 mutation
Triple Negative Breast Cancer
BRCA2 mutation
Triple Negative Breast Cancer
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
BRCA1 mutation
Triple Negative Breast Cancer
BRCA1 mutation
Triple Negative Breast Cancer
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
No biomarker
Leiomyosarcoma
No biomarker
Leiomyosarcoma
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
No biomarker
Soft Tissue Sarcoma
No biomarker
Soft Tissue Sarcoma
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
No biomarker
Sarcoma
No biomarker
Sarcoma
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
eribulin mesylate
Sensitive: A2 - Guideline
eribulin mesylate
Sensitive
:
A2
HER-2 underexpression
Breast Cancer
HER-2 underexpression
Breast Cancer
eribulin mesylate
Sensitive: B - Late Trials
eribulin mesylate
Sensitive
:
B
eribulin mesylate
Sensitive: B - Late Trials
eribulin mesylate
Sensitive
:
B
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
eribulin mesylate
Sensitive: C2 – Inclusion Criteria
eribulin mesylate
Sensitive
:
C2
eribulin mesylate
Sensitive: C2 – Inclusion Criteria
eribulin mesylate
Sensitive
:
C2
PGR expression
Breast Cancer
PGR expression
Breast Cancer
eribulin mesylate
Sensitive: C2 – Inclusion Criteria
eribulin mesylate
Sensitive
:
C2
eribulin mesylate
Sensitive: C2 – Inclusion Criteria
eribulin mesylate
Sensitive
:
C2
HER-2 overexpression
Breast Cancer
HER-2 overexpression
Breast Cancer
eribulin mesylate
Sensitive: C2 – Inclusion Criteria
eribulin mesylate
Sensitive
:
C2
eribulin mesylate
Sensitive: C2 – Inclusion Criteria
eribulin mesylate
Sensitive
:
C2
TLE3 expression
Triple Negative Breast Cancer
TLE3 expression
Triple Negative Breast Cancer
eribulin mesylate
Sensitive: C3 – Early Trials
eribulin mesylate
Sensitive
:
C3
eribulin mesylate
Sensitive: C3 – Early Trials
eribulin mesylate
Sensitive
:
C3
BRCA2 mutation
Triple Negative Breast Cancer
BRCA2 mutation
Triple Negative Breast Cancer
gemcitabine + eribulin mesylate
Resistant: C3 – Early Trials
gemcitabine + eribulin mesylate
Resistant
:
C3
gemcitabine + eribulin mesylate
Resistant: C3 – Early Trials
gemcitabine + eribulin mesylate
Resistant
:
C3
BRCA1 mutation
Triple Negative Breast Cancer
BRCA1 mutation
Triple Negative Breast Cancer
gemcitabine + eribulin mesylate
Resistant: C3 – Early Trials
gemcitabine + eribulin mesylate
Resistant
:
C3
gemcitabine + eribulin mesylate
Resistant: C3 – Early Trials
gemcitabine + eribulin mesylate
Resistant
:
C3
PD-L1 expression
Breast Cancer
PD-L1 expression
Breast Cancer
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
Chr amplification(4)(q22.1)
Leiomyosarcoma
Chr amplification(4)(q22.1)
Leiomyosarcoma
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
Chr del(3)(q14.2)
Leiomyosarcoma
Chr del(3)(q14.2)
Leiomyosarcoma
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
Chr del(11)(q25)
Leiomyosarcoma
Chr del(11)(q25)
Leiomyosarcoma
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
Chr del(2)(q14.1)
Leiomyosarcoma
Chr del(2)(q14.1)
Leiomyosarcoma
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
Chr del(2)(p12)
Leiomyosarcoma
Chr del(2)(p12)
Leiomyosarcoma
eribulin mesylate
Sensitive: C3 – Early Trials
eribulin mesylate
Sensitive
:
C3
eribulin mesylate
Sensitive: C3 – Early Trials
eribulin mesylate
Sensitive
:
C3
Chr del(1)(q44)
Leiomyosarcoma
Chr del(1)(q44)
Leiomyosarcoma
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
Chr amplification(8)(q13.2)
Leiomyosarcoma
Chr amplification(8)(q13.2)
Leiomyosarcoma
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
Chr amplification(8)(q22.2)
Leiomyosarcoma
Chr amplification(8)(q22.2)
Leiomyosarcoma
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
Chr amplification(13)(q13.3)
Leiomyosarcoma
Chr amplification(13)(q13.3)
Leiomyosarcoma
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
Chr amplification(20)(p12.2)
Leiomyosarcoma
Chr amplification(20)(p12.2)
Leiomyosarcoma
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
Chr amplification(4)(q26)
Leiomyosarcoma
Chr amplification(4)(q26)
Leiomyosarcoma
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
ATRX mutation
Leiomyosarcoma
ATRX mutation
Leiomyosarcoma
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
eribulin mesylate
Resistant: C3 – Early Trials
eribulin mesylate
Resistant
:
C3
TP53 mutation
Leiomyosarcoma
TP53 mutation
Leiomyosarcoma
eribulin mesylate
Sensitive: C3 – Early Trials
eribulin mesylate
Sensitive
:
C3
eribulin mesylate
Sensitive: C3 – Early Trials
eribulin mesylate
Sensitive
:
C3
PD-L1 expression
Triple Negative Breast Cancer
PD-L1 expression
Triple Negative Breast Cancer
pembrolizumab + eribulin mesylate
Sensitive: C3 – Early Trials
pembrolizumab + eribulin mesylate
Sensitive
:
C3
pembrolizumab + eribulin mesylate
Sensitive: C3 – Early Trials
pembrolizumab + eribulin mesylate
Sensitive
:
C3
PIK3CA mutation
Breast Cancer
PIK3CA mutation
Breast Cancer
docetaxel + cyclophosphamide + eribulin mesylate
Resistant: C3 – Early Trials
docetaxel + cyclophosphamide + eribulin mesylate
Resistant
:
C3
docetaxel + cyclophosphamide + eribulin mesylate
Resistant: C3 – Early Trials
docetaxel + cyclophosphamide + eribulin mesylate
Resistant
:
C3
^
^
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