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DRUG:

depatuxizumab mafodotin (ABT-414)

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Company:

AbbVie

Drug class:

Microtubule inhibitor, EGFR-targeted antibody-drug conjugate

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estramustine (0)

Nectin-4 ADC (0)

vintafolide (0)

HuMax-AXL-ADC (0)

mebendazole (0)

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EGFR amplification	Glioblastoma	EGFR amplification	Glioblastoma	ABT-414 Sensitive: C2 – Inclusion Criteria ABT-414 Sensitive : C2	ABT-414 Sensitive: C2 – Inclusion Criteria ABT-414 Sensitive : C2
EGFR amplification	Glioma	EGFR amplification	Glioma	ABT-414 Sensitive: C2 – Inclusion Criteria ABT-414 Sensitive : C2	ABT-414 Sensitive: C2 – Inclusion Criteria ABT-414 Sensitive : C2
EGFR overexpression	Triple Negative Breast Cancer	EGFR overexpression	Triple Negative Breast Cancer	ABT 263 + ABT-414 Sensitive: D – Preclinical ABT 263 + ABT-414 Sensitive : D	ABT 263 + ABT-414 Sensitive: D – Preclinical ABT 263 + ABT-414 Sensitive : D