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    DRUG:

    PF-08046054

    i
    Other names: PF-08046054, SGN-PDL1V
    Company:
    Pfizer
    Drug class:
    Microtubule inhibitor, PD-L1-targeted antibody-drug conjugate
    Related drugs:
    2years
    Phase 1 study of SGN-PDL1V, a novel, investigational vedotin antibody–drug conjugate directed to PD-L1, in patients with advanced solid tumors (SGNPDL1V-001, trial in progress). (ASCO 2022)
    Objective response rate will be analyzed by tumor type, dose levels, and schedules. Enrollment for Part A is ongoing at sites in North America and is planned in Europe.
    Clinical • P1 data • PD(L)-1 Biomarker • IO biomarker
    |
    PD-L1 (Programmed death ligand 1)
    |
    PD-L1 expression
    |
    PF-08046054