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DRUG:

RC108

i
Other names: RC108, RC108-ADC
Associations
Company:
Rongchang Pharma
Drug class:
Microtubule inhibitor, c-MET-targeted antibody-drug conjugate
Related drugs:
Associations
5ms
RC108 Combine With Furmonertinib With/Without Toripalimab in Patients With EGFR-mutated NSCLC (clinicaltrials.gov)
P1/2, N=106, Recruiting, RemeGen Co., Ltd. | Not yet recruiting --> Recruiting
Enrollment open
|
PD-L1 (Programmed death ligand 1)
|
PD-L1 expression • EGFR mutation • EGFR L858R • EGFR exon 19 deletion • EGFR T790M • EGFR G719X • EGFR S768I • MET expression • EGFR exon 18 mutation
|
Loqtorzi (toripalimab-tpzi) • Ivesa (furmonertinib) • RC108
1year
New P1/2 trial • Combination therapy • Metastases
|
PD-L1 (Programmed death ligand 1)
|
PD-L1 expression • EGFR mutation • EGFR L858R • EGFR exon 19 deletion • EGFR T790M • EGFR G719X • EGFR S768I • MET expression • EGFR exon 18 mutation
|
Loqtorzi (toripalimab-tpzi) • Ivesa (furmonertinib) • RC108
1year
A Study of RC108-ADC in Subjects With Advanced Digestive System Malignant Tumor (clinicaltrials.gov)
P2, N=240, Recruiting, RemeGen Co., Ltd. | Not yet recruiting --> Recruiting
Enrollment open • Metastases
|
MET (MET proto-oncogene, receptor tyrosine kinase)
|
MET positive
|
RC108
over1year
New P2 trial • Metastases
|
MET (MET proto-oncogene, receptor tyrosine kinase)
|
MET positive
|
RC108
3years
A Study of RC108-ADC in Subjects With Advanced Malignant Solid Tumors (clinicaltrials.gov)
P1, N=32, Recruiting, RemeGen | Not yet recruiting --> Recruiting
Enrollment open
|
MET (MET proto-oncogene, receptor tyrosine kinase)
|
MET positive
|
RC108
over3years
Clinical • New P1 trial
|
MET (MET proto-oncogene, receptor tyrosine kinase)
|
MET positive
|
RC108