Based on the m6A/m5C/m1A-related genes in LUAD, LUAD patients were divided into 2 subtypes, and a m6A/m5C/m1A-related LUAD prognostic model was constructed to provide a reference for the prognosis prediction of LUAD.

5 months ago

Journal

CD8 (cluster of differentiation 8) • CD4 (CD4 Molecule)

Alecensa (alectinib) • Alunbrig (brigatinib) • irinotecan • Torisel (temsirolimus) • saracatinib (AZD0530) • elesclomol (STA-4783) • Emcyt (estramustine)

12ms

Very Long-Term Complete Remission Can Be Achieved in Men With High-Risk Localized Prostate Cancer and a Very High PSA Value: An Analysis of the GETUG 12 Phase 3 Trial. (PubMed, Clin Genitourin Cancer)

Men with apparently localized prostate cancer and a high baseline PSA value have a reasonable chance of being long-term disease-free when treated with curative intent combining systemic and local therapy.

12 months ago

P3 data • Journal

docetaxel • Emcyt (estramustine)

1year

Activity and safety of KEES - an oral multi-drug chemo-hormonal metronomic combination regimen in metastatic castration-resistant prostate cancer. (PubMed, BMC Cancer)

KEES demonstrated meaningful efficacy in heavily pre-treated CRPC patients, especially those with PS 0-1 and lower baseline ALP, and had an acceptable toxicity profile.

1 year ago

Retrospective data • Journal • Metastases

AR (Androgen receptor)

docetaxel • cyclophosphamide • etoposide IV • Emcyt (estramustine)

4years

Evaluation of the Efficacy of Estramustine in Patient With Breast Cancer Progression After Treatment With Aromatase Inhibitor. (clinicaltrials.gov)

P2, N=100, Completed, Institut de Cancérologie de Lorraine | Recruiting --> Completed

4 years ago

Clinical • Trial completion

HER-2 (Human epidermal growth factor receptor 2)

tamoxifen • Emcyt (estramustine)