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Association details:
Biomarker:
RAB5A expression
Cancer:
Breast Cancer
Drug:
Kadcyla (ado-trastuzumab emtansine)
(
Microtubule inhibitor
,
HER2-targeted antibody-drug conjugate
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: B - Late Trials
Source:
Nat Commun
Title:
RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
Published date:
11/05/2021
Excerpt:
RAB5A protein expression correlates with T-DM1 sensitivity in a subset of patients in the Kamilla study…
DOI:
https://doi.org/10.1038/s41467-021-26018-z
Trial ID:
KAMILLA
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